Search Results - neuroscience%2fneurology

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Endonasal Surgical Robot for Sinus and Neurosurgery
Summary Vanderbilt engineers have developed a robotic system for performing sinus and neurosurgery through the nose. This provides a less invasive way to access surgical sites in the sinuses and near the middle of the patient's head, leading to faster recovery times. The robot is modular and sterilizable with detachable cartridge-based instruments....
Published: 7/9/2024   |   Inventor(s):  
Keywords(s): Neuroscience/Neurology
Category(s): Medical Devices, Robotics, General Engineering
Slc5a7 (choline transporter, CHT) BAC Transgenic Mouse
A Bacterial Artificial Chromosome (BAC) containing the mouse Slc5a7 gene was used to make transgenic mice. Mice show elevated choline transporter and acetylcholine levels and increased treadmill endurance. These mice permit the study of elevated presynaptic choline transporter protein in vivo, expressed solely in cholinergic neurons due to the BAC...
Published: 4/18/2016   |   Inventor(s):  
Keywords(s): Analgesic, Cardiovascular, Inflammatory/Immune, Metabolic Disorders/ Diabetes, Neuroscience/Neurology
Category(s): Research Tools
Scn1a Knockout Mouse Genetic Model of Epilepsy
This is a unique genetically modified strain of mice that models Dravet syndrome, a severe infant-onset epileptic encephalopathy. They are maintained on apure 129S6/SvEvTac genetic background to facilitate genetic studies.References:Miller AR, Hawkins NA, McCollom CE, Kearney JA (2014) Mapping genetic modifiers of survival in a mouse modelof Dravet...
Published: 5/31/2023   |   Inventor(s):  
Keywords(s): Cardiovascular, Neuroscience/Neurology
Category(s): Research Tools
Small Molecule mGlu3 NAMs as Therapeutics for CNS Disorders
About VCNDDThe Vanderbilt Center for Neuroscience Drug Discovery (VCNDD) has a mission to promote the translation of advances in basic science towards novel therapeutics. They have recruited faculty and staff with experience at over 10 different pharmaceutical companies to ensure a diverse set of approaches, techniques and philosophies to advancing...
Published: 1/23/2024   |   Inventor(s):  
Keywords(s): Neuroscience/Neurology
Category(s): Therapeutics
GluN2B Floxed Mice (also called NR2B, glutamate receptor 2B)
Allows for targeted deletion of the GluN2B subunit of NMDA receptors in specific cells or at specific times during development, juvenile, or adult stages. C57BL6/J background.
Published: 5/31/2023   |   Inventor(s): Eric Delpire
Keywords(s): Neuroscience/Neurology
Category(s): Research Tools
HEK293 Cell Line with Stable Expression of Drosophila Serotonin Re-Uptake Transporter
This research targets SERT.
Published: 9/22/2015   |   Inventor(s): Randy Blakely, Hyman Niznik
Keywords(s): Neuroscience/Neurology
Category(s): Research Tools
Mouse Model for Cardiovascular/Autonomic Disorders
This research targets CHT.
Published: 10/5/2015   |   Inventor(s): Randy Blakely, Brett English, Mihaela Bazalakova
Keywords(s): Cardiovascular, Neuroscience/Neurology
Category(s): Research Tools