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Search Results - nancy+booth
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Use of Cucurbitacins and Withanolides for the Treatment of Cancer
Abstract: Certain members of the cucurbitacin and Withanolide family have been identified that can sensitize some tumor cell lines to cell death (apoptosis) on subsequent exposure of the cells to pro-apoptotic receptor agonists (PARAS) of the TRAIL "death receptors". These PARAS include TRAIL itself, and agonist antibodies to two of its receptors death...
Published: 5/22/2024
|
Inventor(s):
Thomas Sayers
,
Kirk Gustafson
,
Karen Erickson
,
Alan Brooks
,
Curtis Henrich
,
Nancy Booth
Keywords(s):
cucurbitacin
,
Immunotherapy
,
mapatumamab
,
TRAIL
,
withanolide
Category(s):
Application > Therapeutics
,
TherapeuticArea > Oncology
,
Collaboration Sought > Licensing