Search Results - muscular+dystrophy

3 Results Sort By:
Rapid and Sensitive Detection of Nucleic Acid Sequence Variations
The ability to easily detect small mutations in nucleic acids, such as single base substitutions, can provide a powerful tool for use in cancer detection, perinatal screens for inherited diseases, and analysis of genetic polymorphisms such as genetic mapping or for identification purposes. Current approaches make use of the mismatch that occurs between...
Published: 4/8/2024   |   Inventor(s): Kenji Adzuma, Kiyoshi Mizuuchi, Katsuhiko Yanagihara
Keywords(s): (4)r syndrome, AC6XXX, ACXXXX, AXXXXX, C syndrome, CA1AXX, CA1XXX, CAXXXX, Chromosome 4 ring syndrome, Chromosome 6 ring syndrome, Chromosome 7 ring syndrome, CXXXXX, Cystic fibrosis, Detection, DNA, Fragile X syndrome, G syndrome, Genetic, Huntington disease, Huntington disease; Huntington's disease, Hypertelorism with esophageal abnormality and hypospadias, IA6XXX, IAXXXX, Insertion, IXXXXX, Method, Mismatch-Targeted, Muscular dystrophy, Mutations, N syndrome, R(6) syndrome, R(7) syndrome, Syndrome X, Transposon, W syndrome, W syndrome; Syndrome W
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Diagnostics, Application > Research Materials, Application > Therapeutics, TherapeuticArea > Oncology
2020-781 GENE THERAPY VECTORS FOR TREATING LIMB GIRDLE MUSCULAR DYSTROPHY
Researchers in the Departments of Neurology at UCLA and the University of Washington have developed a novel AAV gene therapy that treats limb-girdle muscular dystrophy type R1/2A (LGMD2A), an as of yet unmet target.BACKGROUND:Muscular dystrophies are a group of muscle diseases caused by mutations in a persons’ genes. Mutations within the calpain3...
Published: 7/19/2023   |   Inventor(s): Melissa Spencer, Irina Kramerova, Steve Hauschka, Jeffrey Chamberlain
Keywords(s): Gene Therapy, Muscular Dystrophy
Category(s): Therapeutics > Gene Therapy And Editing
Treatment for Muscle Atrophy and for Enhancing Muscle Growth
An mRNA based therapeutic that provides for increased hepatic production of follistatin Background Muscle atrophy is a detrimental and often severely debilitating disease state whose etiology lies within a myriad of disease states ranging from AIDS, sepsis, cardiac failure, muscular dystrophies, cancer, and the natural process of aging. The extent...
Published: 6/10/2024   |   Inventor(s): Oleh Taratula, Canan Schumann, Olena Taratula, Adam Alani
Keywords(s): atrophy, growth, mRNA carrier, mRNA delivery, muscle, Muscular Dystrophy, wasting
Category(s): Therapeutics