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Search Results - mek4
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Covalent
MEK4
Inhibitors for Targeted Cancer Therapy
NU 2025-154 INVENTORS Karl Scheidt* Gina Connors SHORT DESCRIPTION This technology introduces novel covalent inhibitors of
MEK4
, built upon previously-developed reversible inhibitors (see NU2019-059 and NU2021-217). A covalent inhibition strategy offers enhanced potency, selectivity, and prolonged duration of action compared to reversible...
Published: 10/20/2025
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Inventor(s):
Keywords(s):
Cancer/Oncology
,
Covalent Inhibition
,
Kinase Inhibitor
,
MEK4
,
MEK7
Category(s):
Life Sciences > Therapeutics