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Search Results - mashelfatema+saifuddin
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Predicting off-target activity of CRISPR-Cas9 complexes
Problem CRISPR-Cas9 is originally a bacterial defense system that uses a guide-RNA to target and nucleases to cut foreign nucleic acids. Recently, these protein-RNA complexes have taken the genome editing world by storm since the revolutionary discovery was made that they could be used as genetic editing tools. By reprogramming the guide-RNA, the Cas9...
Published: 11/1/2023
|
Inventor(s):
Ilya Finkelstein
,
Cheulhee Jung
,
John Hawkins
,
Stephen Jones
,
James Rybarski
,
Mashelfatema Saifuddin
,
Cagri Savran
,
Andrew Ellington
,
William Press
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Life sciences > Research tools > Tool/assay/screening platform