Search Results - luyi+tang

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Low-Cost Mechanically Robust Silica Aerogel Technology
A low-cost mechanically robust silica aerogel technology enhances fiber-based building insulation R-value performance, soundproofing, thermal barrier textiles fabrics, ceramic foams, papers and composites thereof. Background: Energy efficiency in buildings, aerospace, extreme environments and many other sectors seek low cost, scalable, lightweight...
Published: 7/24/2026   |   Updated: 7/24/2026   |   Inventor(s): Shenqiang Ren, Lu An
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Energy Conservation, Technology Classifications > Materials and Chemicals, Technology Classifications > Nanotechnology
Microbial de Novo Biosynthesis of Rare Cannabinoids (UCLA Case No. 2025-200)
UCLA researchers in the department of Chemical and Biomolecular Engineering have developed a microbial de novo biosynthesis platform that enables scalable production of rare cannabinoids with enhanced receptor affinity from simple sugar feedstocks. BACKGROUND: Cannabinoids are bioactive natural products that interact with the human endocannabinoid...
Published: 7/20/2026   |   Updated: 6/2/2026   |   Inventor(s): ikechukwu okorafor, Yi Tang
Keywords(s):  
Category(s): Therapeutics > Cardiovascular, Therapeutics > CNS and Neurology, Materials > Fabrication Technologies, Chemical > Synthesis, Chemical > Chemical Processing & Manufacturing
Aptamer-based field diagnostics for infectious PRRSV and PEDV detection
Background Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) and Porcine Epidemic Diarrhea Virus (PEDV) are two of the most economically destructive viruses impacting the global swine industry. These pathogens cause severe illness and death in pig populations, leading to reduced productivity, increased veterinary expenses, and trade restrictions....
Published: 3/11/2026   |   Updated: 3/11/2026   |   Inventor(s): Yi Lu, Whitney Lewis
Keywords(s):  
Category(s): Life sciences > Agriculture > Animal/veterinary, Life sciences > Diagnostic
DNAzyme-based biosensor technology for selective and real-time detection of potassium ions in biological systems
Background The ability to monitor potassium ion (K+) dynamics is of critical importance, particularly in the context of cancer research and neurobiology. Potassium ions play a fundamental role in maintaining cellular homeostasis, regulating membrane potential, and influencing processes such as cell proliferation, apoptosis, and immune responses. Disruptions...
Published: 1/27/2026   |   Updated: 1/27/2026   |   Inventor(s): Yi Lu, Zhenglin Yang, Xiangli Shao, Yuting Wu
Keywords(s):  
Category(s): Life sciences > Biomaterials, Life sciences > Research tools > Tool/assay/screening platform
DNAzyme-seq: a single-cell metal ion and transcriptome profiling platform
Background Metal ions such as zinc, copper, and calcium play indispensable roles in nearly every facet of cellular physiology, from enzymatic catalysis to signal trans­duction. However, conventional single-cell transcriptomics has largely over­looked the contribution of metal cofactors to gene expression, metabolism, and disease progression....
Published: 1/13/2026   |   Updated: 12/4/2025   |   Inventor(s): Yi Lu, Mandira Banik, Valeria Garcia, Ishika Rashed
Keywords(s):  
Category(s): Life sciences > Research tools > Tool/assay/screening platform, Life sciences > Immunology > Genomics/genetics
Biocompatible photoenzymatic system for selective C–H fluorination
Background C–H fluorination plays a central role in pharmaceutical and agrochemical synthesis, as the introduction of fluorine often enhances a molecule's metabolic stability, potency, and bioavailability. Over 20% of approved drugs contain fluorinated functional groups, underscoring the demand for efficient and selective fluorination methods....
Published: 1/13/2026   |   Updated: 7/31/2025   |   Inventor(s): Yi Lu, Yu Zhou
Keywords(s):  
Category(s): Life sciences > Metabolic engineering
DNA-based sensors for live-cell mapping of metabolite- and metal ion-protein interactions
Background Understanding how metabolites and metal ions interact with proteins inside living cells is essential for decoding cellular signaling, metabolic regulation, and disease mechanisms. These small molecules function as cofactors, second messengers, and allosteric regulators, orchestrating critical pathways that govern cell behavior. However,...
Published: 4/2/2026   |   Updated: 6/16/2025   |   Inventor(s): Yi Lu, Mandira Banik
Keywords(s):  
Category(s): Life sciences > Research tools > Tool/assay/screening platform, Life sciences > Immunology > Genomics/genetics
Artificial nitrogenase enzymes for ambient-condition, decentralized ammonia production
Background Ammonia synthesis is foundational to global agriculture and chemical manufacturing, providing the primary source of fixed nitrogen for fertilizers, polymers, and pharmaceuticals. Traditional ammonia production through the Haber-Bosch process, however, operates under extreme conditions—temperatures exceeding 400°C and pressures...
Published: 1/13/2026   |   Updated: 6/16/2025   |   Inventor(s): Yi Lu, Hirbod Heidari, Markus Ribbe, Yilin Hu, Chi Chung Lee, Evan Mirts
Keywords(s):  
Category(s): Life sciences > Therapeutics > Synthetic biology, Life sciences > Metabolic engineering
Auto Hoist Stabilization System with Wireless Sync
THE CHALLENGE Modern helicopter rescue operations require hoist operations that are safe, fast, and stable—particularly when suspended payloads swing dangerously due to wind, rotor wash, or sudden movements. These swings not only pose serious safety risks but also slow down mission times and increase stress on crews. Existing systems often rely...
Published: 10/22/2025   |   Updated: 5/13/2025   |   Inventor(s): David Reineke, Kyle Nguyen, Luyi Tang, Walter Lacarbonara, Mary Lanzerotti, Rui Peng
Keywords(s):  
Category(s): Technology Classifications > Engineering, Technology Classifications > Architecture/Building, Technology Classifications > Mining and Recycling, Technology Classifications > Electronics
DNAzyme sensor for selective manganese ion detection in biological systems
A selective DNAzyme-based fluorescent sensor detects manganese ions in cells by lighting up when Mn²⁺ binds, allowing precise monitoring of manganese levels for biological research and potential therapies. Background Manganese (Mn²⁺) is an essential trace element integral to numerous biological processes, acting as a vital cofactor for enzymes...
Published: 1/13/2026   |   Updated: 1/31/2025   |   Inventor(s): Yi Lu, Zhenglin Yang, Huanhuan Fan
Keywords(s):  
Category(s): Life sciences > Biomaterials
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