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Search Results - life+sciences+%3e+biomaterials
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A platform of DNA-functionalized protein nanostructures for enhancing and delivering catalytic enzyme activity
This technology boosts the catalytic activity of heme-containing proteins by densely attaching short DNA strands, creating stable, biocompatible constructs that autonomously enter cells, enabling advanced therapeutic, antimicrobial, and biosensing applications without genetic modification or toxic delivery agents. Background Enzymes, particularly...
Published: 7/22/2026
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Updated: 7/22/2026
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Inventor(s):
Devleena Samanta
,
Neha Satish
,
Seungheon Lee
,
Rupali Chowdhry
Keywords(s):
Category(s):
Life sciences > Biomaterials
Biological Expression Platform for Producing and Engineering Electrically Conductive Protein Nanowires and Bioelectronic Materials
This technology uses engineered Shewanella oneidensis bacteria to rapidly produce highly conductive protein nanowires for sustainable energy, bioelectronics, and sensor applications, offering a scalable, cost-effective, and eco-friendly alternative to synthetic conductive materials. Background The field of bioelectronics and sustainable energy harvesting...
Published: 7/10/2026
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Updated: 7/10/2026
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Inventor(s):
Andrew Ellington
,
Eric Szmuc
,
Benjamin Keitz
,
David Walker
,
Marcel Reed
Keywords(s):
Category(s):
Life sciences > Biomaterials
,
Physical sciences > Energy > Renewable, green, or transitional energy
Nucleopeptide hybrid hydrogels
Eliminates Xenogeneic Matrix Variability: Synthetic Hydrogel Delivers Reproducible 3D hiPSC Culture This technology is a customizable, fully synthetic hydrogel made from self-assembling nucleopeptides, designed to mimic the natural cell environment, support stem cell growth, deliver growth factors and nucleic acids, and replace animal-derived cell...
Published: 5/12/2026
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Updated: 5/12/2026
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Inventor(s):
Laura Suggs
,
Haidyn Ogg
Keywords(s):
Category(s):
Life sciences > Research tools > Reagent
,
Life sciences > Biomaterials
A multiplexed CRISPR genome editing platform for simultaneous gene disruption in neurons
SPADA is a CRISPR-based genome editing system that uses engineered viruses to efficiently and specifically disrupt multiple genes in targeted brain cells, enabling precise modeling of complex genetic brain disorders in animals. Background The field of neurogenetics relies heavily on genome editing to understand the mechanisms of complex psychiatric...
Published: 6/10/2026
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Updated: 4/27/2026
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Inventor(s):
Lief Fenno
,
Yeonha Ju
Keywords(s):
Category(s):
Life sciences
,
Life sciences > Research tools > Tool/assay/screening platform
,
Life sciences > Biomaterials
Engineered yeast strains for enhanced conversion of xylose to ethanol from lignocellulosic biomass
This technology uses genetically engineered yeast with an improved xylose isomerase enzyme to efficiently convert xylose from plant biomass into ethanol, greatly boosting biofuel production rates and yields for sustainable energy applications. Background Lignocellulosic biomass, such as agricultural residues and woody materials, represents a vast...
Published: 4/9/2026
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Updated: 4/9/2026
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Inventor(s):
Hal Alper
,
Sunmi Lee
Keywords(s):
Category(s):
Life sciences > Agriculture
,
Life sciences > Research tools > Reagent
,
Life sciences > Biomaterials
Liquid-phase gas nanotransducers as an ultrasound actuator and imaging reporter
Background Ultrasound imaging and actuation technologies play a critical role in modern medicine, however applications rely heavily on the use of gas-filled agents, such as microbubbles and gas vesicles, which enhance ultrasound contrast and facilitate mechanical effects in biological tissues. The demand for improved imaging resolution, deeper tissue...
Published: 3/12/2026
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Updated: 3/12/2026
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Inventor(s):
Huiliang Wang
,
Wenliang Wang
Keywords(s):
Category(s):
Life sciences > Biomaterials
,
Life sciences > Medical technology
Non-invasive sono-optogenetic platform for deep brain neural modulation
Background Neuromodulation technologies such as deep brain stimulation and optogenetics have transformed the treatment of neurological disorders by enabling targeted control of dysfunctional neural circuits, yet their clinical adoption is limited by invasive surgical requirements, off-target effects, poor penetration depth, and lack of cell-type specificity....
Published: 5/27/2026
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Updated: 3/11/2026
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Inventor(s):
Huiliang Wang
,
Wenliang Wang
,
Ilia Pyatnitskiy
Keywords(s):
Category(s):
Life sciences > Biomaterials
,
Life sciences > Therapeutics
Engineered prodrug with tumor-selective delivery for targeted glycolysis inhibition.
Engineered prodrug with tumor-selective delivery for targeted glycolysis inhibition A conjugate of 2-deoxy-D-glucose and a fatty acid forms albumin-binding nanoparticles that enter cancer cells via glucose and fatty acid transporters, inhibit glycolysis, and induce tumor-selective cell death with enhanced potency and targeting. Background The...
Published: 5/27/2026
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Updated: 2/23/2026
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Inventor(s):
Cassandra Callmann
,
Sungjin Jeon
Keywords(s):
Category(s):
Life sciences > Biomaterials
,
Life sciences > Therapeutics > Drug delivery
DNAzyme-based biosensor technology for selective and real-time detection of potassium ions in biological systems
Background The ability to monitor potassium ion (K+) dynamics is of critical importance, particularly in the context of cancer research and neurobiology. Potassium ions play a fundamental role in maintaining cellular homeostasis, regulating membrane potential, and influencing processes such as cell proliferation, apoptosis, and immune responses. Disruptions...
Published: 1/27/2026
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Updated: 1/27/2026
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Inventor(s):
Yi Lu
,
Zhenglin Yang
,
Xiangli Shao
,
Yuting Wu
Keywords(s):
Category(s):
Life sciences > Biomaterials
,
Life sciences > Research tools > Tool/assay/screening platform
Precision-crafted membranes for enhanced separation efficiency
This technology enables fast, scalable production of durable biomimetic membranes by co-depositing polymers and nanosheets with embedded channels, then covalently crosslinking them, creating high-performance filters for water purification and molecular separations with enhanced permeability and selectivity. Background Membrane-based separation technologies...
Published: 1/13/2026
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Updated: 12/5/2025
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Inventor(s):
Manish Kumar
,
Ronald Vogler
,
Raman Dhiman
,
Katherine Kimball
,
Dominic Bujanos
Keywords(s):
Category(s):
Life sciences > Biomaterials
,
Physical sciences > Materials > Membranes
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