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Composite Probes and Use Thereof in Super Resolution Microscopy
The technology is in the field of fluorescence microscopy. More specifically, the invention describes and claims the composite probes for super resolution optical techniques using super resolution via transiently activated quenchers (STAQ). The composite probes include a donor moiety and an acceptor moiety joined by a linker. The acceptor moiety, when...
Published: 10/28/2024   |   Inventor(s): Gary Griffiths, Jay Knutson
Keywords(s): AC3XXX, ACTIVATED, ACXXXX, AXXXXX, Concept, LABELS, MICROSCOPY, Patent Category - Chemistry, Quenchers, STAQ, Superresolution, Transiently, Via
Category(s): Collaboration Sought > Collaboration
Genetic incorporation of tetrazine amino acids and use in bioorthogonal ligations
Technology Description Ideal bioorthogonal reactions containing high reaction rates, high selectivity and high stability would allow for stoichiometric labeling of biomolecules in minutes and eliminate the need to washout excess labeling reagent. Currently no general method exists for controlled stoichiometric or sub-stoichiometric labeling of proteins...
Published: 6/18/2024   |   Inventor(s): Ryan Mehl, Robert Blizzard
Keywords(s): Biological & Environmental Engineering, Biomedical, Biotechnology, Diagnostic, Labels, Protein Polymer Hybrids, Research Tools
Category(s): Diagnostics