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Repurposing Tamoxifen to treat lethal E. coli infections
ProblemOver 100,000 people suffer from Shiga toxin-producing E. coli infections every year which cause gastrointestinal illness. In 5% to 15% of cases, these toxins enter the bloodstream, which can result in fatal renal disease. These infections are currently untreatable, as traditional antibiotics induce higher toxin concentrations and worsen illness....
Published: 11/1/2023   |   Inventor(s): Somshuvra Mukhopadhyay, Andrey Selyunin
Keywords(s): Antimicrobials, Digestive disease, Drug development, Drugs, Gastroenterology, Infectious disease, Kidney disease, Pharmaceuticals
Category(s): Life sciences > Therapeutics > Small molecule