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Search Results - kenan+christoph+garcia
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Catch Bond-Enhanced Human T Cell Receptors Targeting Prostatic Acid Phosphatase on HLA-A*02:01 (UCLA Case No. 2025-138)
UCLA researchers from the Department of Microbiology, Immunology, and Molecular Genetics and Stanford researchers from the Department of Molecular and Cellular Physiology have developed novel enhanced T cell receptors engineered to specifically recognize prostatic acid phosphatase, offering a powerful and precise immunotherapeutic strategy for prostate...
Published: 9/19/2025
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Inventor(s):
Owen Witte
,
Zhiyuan Mao
,
John Lee
,
Kenan Christoph Garcia
Keywords(s):
Category(s):
Therapeutics > Oncology
,
Therapeutics > Immunology And Immunotherapy
HIGH-THROUGHPUT FORCE-DEPENDENT CELLULAR RESPONSE ASSAY USING SPECTRALLY ENCODED SMART BEADS
HIGH-THROUGHPUT FORCE-DEPENDENT CELLULAR RESPONSE ASSAY USING SPECTRALLY ENCODED SMART BEADS Researchers at Stanford have developed a technology that uses biomechanical force to initiate T-cell triggering in a high throughput method, facilitating the exploration of the force- and sequence-dependent landscape of T-cell responses. Adaptive immunity...
Published: 3/17/2023
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Inventor(s):
Xiang Zhao
,
Adam White
,
Polly Fordyce
,
Yinnian Feng
,
K Garcia
Keywords(s):
Catch Bond
,
High-Throughput Mechanobiology
,
Ligand Discrimination
,
Mechanotransduction
,
Single-Cell Microfluidics
,
Spectrally Encoded Beads
,
T-Cell Activation
,
T-Cell Biophysics
,
T-Cell Receptor
Category(s):
Technology Classifications > Biology