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Search Results - joel+garcia
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Method of Treating Acute Lung Injury Using Sphingosine 1 Phosphate Analogs Or Sphingosine 1 Phosphate Receptor Agonists
This invention describes a method to treat and reduce the risk for acute lung injury (ALI) associated with radiation, infection, trauma, and other environmental-related lung injury. The method described involves the administration of analogs or derivatives of a Sphingosine 1 Phosphate (S1P) receptor agonists that have similar properties of S1P that...
Published: 4/3/2023
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Inventor(s):
Joe Garcia
,
Steven Dudek
Keywords(s):
Category(s):
Technology Classifications > Life Sciences > Therapeutics
eNAMPT mAb for Treatment of Acute Cardiac Ischemia and Infarction
This invention is a highly novel theranostic target, extracellular nicotinamide phosphoribosyl-transferase (eNAMPT), that can afford specific detection and treatment of post-infarct inflammation-mediated myocardial injury based on an eNAMPT-neutralizing humanized monoclonal antibody (mAb). Background: Worldwide, cardiovascular diseases are responsible...
Published: 7/6/2023
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Inventor(s):
Joe Garcia
,
Diego Martin
,
Zhonglin Liu
Keywords(s):
Category(s):
Technology Classifications > Life Sciences
Natural Treatment for Ventilation Induced Lung Injury
This invention is the use of bixin, a NRF2 inducer, to reduce lung damage caused by mechanical ventilation. Bixin was found to suppress inflammatory mediators, reduce alveolar capillary leakage, and protect against DNA oxidative damage. Background: Mechanical ventilation is used to assist patients who have difficulty breathing spontaneously in conditions...
Published: 11/16/2023
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Inventor(s):
Donna Zhang
,
Georg Wondrak
,
Joe Garcia
,
Ting Wang
Keywords(s):
Category(s):
Technology Classifications > Life Sciences > Therapeutics
Expression of Nicotinamide Phosphoribosyltransferase Mediated Genes Predicts Recurrence-free Survival in Lung and Breast Cancers
The technology is a prognostic cancer gene assay for lung and breast cancer that utilizes a new biomarker. The technology fills a current need for better prognosis tools for triple negative breast cancer tumors and provides a new discovery in gene expression profiling. Background: This biomarker, NAMPT (nicotinamide phosphoribosyltransferase), is...
Published: 4/3/2023
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Inventor(s):
Joe Garcia
Keywords(s):
Category(s):
Technology Classifications > Life Sciences > Diagnostics
Next Generation MRI Contrast Imaging Agent
WSU has developed a new class of contrast agents that are effective at ultra-high field strengths (>3 tesla) in magnetic resonance imaging (MRI) where current clinical agents severely decline in effectiveness. Our new agents are based on the metal Eu(II) which is novel compared to current agents that are based on Gd(III). The difference between the...
Published: 11/8/2021
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Inventor(s):
Matthew Allen
,
Nipuni Gamage
,
Yujiang Mei
,
Joel Garcia
,
Jeremiah Moore
Keywords(s):
Compound
,
Diagnostic
,
Imaging
,
MRI
,
Positive Imaging Agent
Category(s):
Imaging
,
Chemicals
,
Life Science
,
MRI
,
Physical Sciences
,
Specialty compounds