Search Results - joe+ramos

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Natural product-based anti-cancer agents: aza-Englerin analogues
Abstract: Chemotherapy resistance in a wide array of cancers is often associated with enhanced glucose uptake and dysregulation of the insulin signaling pathway.  Therapeutics capable of inhibiting insulin signaling would be valuable as a stand-alone treatment and for sensitizing resistant tumors to standard chemotherapy regiments.  Researchers at NCI’s...
Published: 7/3/2024   |   Inventor(s): Willaim Chain, John Beutler, William Figg, Joe Ramos, Florian Suizmaier, Zhenwu Li, Daniel Fash, Ian Talisman, Cody Peer
Keywords(s): Ewing, Glycolytic, insulin, Resistance, Sarcoma
Category(s): Application > Therapeutics, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Oncology
Titanocene-Gold Derivatives as Chemotherapeutics for Renal Cancer
Gold complexes have shown promise in cancer chemotherapy, with several compounds having overcome cisplatin resistance of specific cancer cells, furthering their appeal. Early-transition metal complexes, particularly titanocene-based complexes, are another class of compounds being explored for cancer chemotherapy. Recently novel metallodrugs have been...
Published: 10/6/2023   |   Inventor(s): Joe Ramos, Maria Contel, Jacob Fernandez-Gallardo, Benelita Elie
Keywords(s):  
Category(s): Healthcare