Search Results - jianwei+zhu

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Abstract: This technology provides improved processes for production and purification of nucleic acid-containing compositions, such as non-naturally occurring viruses, for example, recombinant polioviruses that can be employed as oncolytic agents. Some of the improved processes relate to improved processes for producing viral DNA template. Also provided...

Published: 8/14/2024 | Inventor(s): Jianwei Zhu, Samir Shaban, Yueqing Xie, Trevor Broadt, Gautam ("George") Mitra

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Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Therapeutics, TherapeuticArea > Oncology

Vascularized bone construct using dual 3D bio-printing & regional bioactive factors

GW researchers generated a vascularized and highly osteogenic bone construct with a biphasic structure using a multiple 3D printing platform. Traditional tissue engineering techniques face major obstacles in creating multiple tissue structures and vascularization of tissues. 3D bioprinting allows for control over the location of cells and biomaterials;...

Published: 7/30/2024 | Inventor(s): Haitao Cui, Wei Zhu, Lijie Zhang

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Category(s): Technology Classifications > Medical Devices > Regenerative Medicine

3D printed vascularized tissue scaffold with extracellular matrix triggered growth factor release

Vas-Scaf” is a 3D bio-printed vascularized bone scaffold perfused with osteogenic and angiogenic growth factors. Artificial bone grafts lacking vascularization fail due to poor integration of new tissues with the host and death of interior bone tissues. Bone and blood vessel tissues require different support structures and different biochemical...

Published: 9/11/2024 | Inventor(s): Haitao Cui, Wei Zhu, Benjamin Holmes, Lijie Zhang

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Category(s): Technology Classifications > Therapeutics, Technology Classifications > Therapeutics > Nanoparticles, Technology Classifications > Industrial or Consumer Tech > Materials

3D Shape Memory Scaffolds for Tissue Engineering

Over 120,000 patients are currently waiting for lifesaving organ and tissue transplants. Tissue engineering has the potential to innovate transplant and minimally invasive surgery by creating tissue substitutes from biopolymers with human stem cells. GW researchers developed a plant oil infused biopolymer with unique characteristics that are highly...

Published: 7/30/2024 | Inventor(s): Shida Miao, Wei Zhu, Nathan Castro, Lijie Zhang

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Category(s): Technology Classifications > Industrial or Consumer Tech > Materials, Technology Classifications > Therapeutics > Cells, Technology Classifications > Therapeutics > Small Molecules

Hybrid Plasmonic Platform for Directing and Controlling Nanostructure Growth

Low-Heat, Bottom-Up Approach Can Produce Metal, Polymer or Bio-Molecule Structures for Catalysis, Biosensors, Electronic Devices and MoreThis surface plasmon mediated chemical solution deposition method uses surface plasmon resonance to deposit nanoparticles in the liquid phase at room temperature to direct and control nanostructure growth. Plasmonic...

Published: 6/27/2021 | Inventor(s): Wei Wei, Jingjing Qiu

Keywords(s): Catalysts, nanoparticle synthesis, Plasmonic, Thin Films

Category(s): Technology Classifications > Engineering > Chemical, Technology Classifications > Engineering > Materials

Bi-Functional RGD Peptide and a Co-Signaling Mechanism to Promote Therapeutic Angiogenesis

Bi-Functional RGD Peptide to Promote Therapeutic Angiogenesis, Treat Ischemic Diseases Technology: While previous studies have focused on the identification of biological ligands to improve the functions of endothelial cells, MUSC and Clemson University researchers have combined modern bioinformatics and a newly established peptide functionalized...

Published: 3/23/2023 | Inventor(s): Chung-Jen (James) Chou, Ying Mei, Jia Jia

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Category(s): BioPharma