Search Results - haitao+cui

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3D Bioprinting of Cardiac Patch with Anisotropic and Perfusable Architecture for the Repair of Damaged Cardiac Muscle

This technology includes a novel cardiac patch which was 3D printed to repair damaged cardiac tissue. Based on biological and anatomical understanding of myocardial tissue, a novel 3D bioprinting technique was developed to directly fabricate the cellularized and vascularized cardiac patch with anisotropic fiber and perfusable vessel architecture. The...

Published: 8/12/2024 | Inventor(s): Lijie Zhang, Haitao Cui, Yimin Huang

Keywords(s):

Category(s): Application > Medical Devices, Application > Research Materials, Collaboration Sought > Licensing, ResearchProducts > Research Equipment, TherapeuticArea > Cardiology

Self-morphing 4D-printed programmable culture substrate for controlling neural stem cell growth

Neural stem cells (NSCs) exhibit great promise for treating neurodegenerative diseases and injuries. Treatments will rely on efficient proliferation and differentiation of NSCs into neurons with therapeutic characteristics. Static 2D and 3D microenvironment culture substrates fail to cater to the dynamic cell needs, resulting in sub-optimal, inefficient...

Published: 9/11/2024 | Inventor(s): Shida Miao, Haitao Cui, Lijie Zhang

Keywords(s):

Category(s): Technology Classifications > Research Tools > Buffers and Media

Thick 3D Bioprinted Cardiac Patch with Anisotropic and Perfusable Vessels

GW researchers fabricated a vascularized patch of cardiac tissue suitable for cardiac regeneration using 3D bioprinting. Cardiovascular disease involving myocardial infarction is a major cause of morbidity and mortality worldwide. Following myocardial infarction, adult cardiac tissue cannot significantly repair or regenerate itself. Current therapies...

Published: 7/30/2024 | Inventor(s): Lijie Zhang, Haitao Cui, Yimin Huang

Keywords(s):

Category(s): Technology Classifications > Medical Devices > Cardiology

Vascularized bone construct using dual 3D bio-printing & regional bioactive factors

GW researchers generated a vascularized and highly osteogenic bone construct with a biphasic structure using a multiple 3D printing platform. Traditional tissue engineering techniques face major obstacles in creating multiple tissue structures and vascularization of tissues. 3D bioprinting allows for control over the location of cells and biomaterials;...

Published: 7/30/2024 | Inventor(s): Haitao Cui, Wei Zhu, Lijie Zhang

Keywords(s):

Category(s): Technology Classifications > Medical Devices > Regenerative Medicine

3D printed vascularized tissue scaffold with extracellular matrix triggered growth factor release

Vas-Scaf” is a 3D bio-printed vascularized bone scaffold perfused with osteogenic and angiogenic growth factors. Artificial bone grafts lacking vascularization fail due to poor integration of new tissues with the host and death of interior bone tissues. Bone and blood vessel tissues require different support structures and different biochemical...

Published: 9/11/2024 | Inventor(s): Haitao Cui, Wei Zhu, Benjamin Holmes, Lijie Zhang

Keywords(s):

Category(s): Technology Classifications > Therapeutics, Technology Classifications > Therapeutics > Nanoparticles, Technology Classifications > Industrial or Consumer Tech > Materials