Search Results - igor+kaltashov

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Antibody for Treatment and Diagnosis of Vaccine-induced Immune Thrombotic Thrombocytopenia (VITT)
­ rss.Item1Header>APPLICATIONS Applications include: Use in the diagnosis and study of VITT, through the detection and measurement of the antibodies; and Clinical applications as a treatment method for patients with VITT and potentially heparin-induced thrombocytopenia (HIT). Advantages include: First VITT anti-PF4 antibody to...
Published: 5/29/2024   |   Inventor(s): Igor Kaltashov, Daniil Ivanov, Ishac Nazy, Donal Arnold, John Kelston, Nikola Ivetic
Keywords(s):  
Category(s): Diagnostic technology
Protein Conjugates Based on Bacteriostatic Proteins as Antimicrobial Drugs for Treating Infections in the Central
The incidence of brain and central nervous system (CNS) infections is rising at an alarming rate, while treatment options remain very limited. Only about 5% of existing small-molecule medicines can cross the blood-brain barrier (BBB), and none of the currently approved protein therapeutics are capable of doing so. With increasing resistance of pathogens...
Published: 1/18/2022   |   Inventor(s): Igor Kaltashov, Son Nguyen, Cedric Bobst
Keywords(s):  
Category(s): Therapeutics & prevention
High-accuracy Temperature-controlled Electrospray Ionization Source for Characterization of Heat-induced
This technology provides a temperature-controlled electrospray ionization (ESI) source that allows for highly precise and accurate characterization of the thermal stability and aggregation of proteins by ESI mass spectrometry (MS). The ESI source was designed to eliminate artifacts that interfere with the detection of temperature-induced changes of...
Published: 1/18/2022   |   Inventor(s): Guanbo Wang, Rinat Abzalimov, Igor Kaltashov
Keywords(s):  
Category(s): Biotechnology, Devices, Engineering, Research tools