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Dual Inhibition of RNA Polymerase I and III as a Novel Strategy for Targeting Ribosome Biogenesis in Cancer
A specially designed peptide blocks two key enzymes needed for ribosome production in cancer cells, shutting down their protein-making machinery and offering a new, more effective way to treat cancer and prevent drug resistance. Background: Ribosome biogenesis is a fundamental cellular process involving the coordinated synthesis of ribosomal RNA...
Published: 2/19/2026   |   Inventor(s): Haleigh Pascual, Bruce Knutson
Keywords(s): Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Therapeutics and Vaccines