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Search Results - haiyue+xu
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Thin film freezing technology for stable dry formulations of mRNA therapeutics
A thin film freezing method transforms mRNA and lipid nanoparticles into stable dry powders that retain their effectiveness and size. This eliminates the need for ultra-cold storage, allowing the powders to be inhaled or reconstituted, improving the distribution of mRNA therapies. Background mRNA therapeutics represent a groundbreaking advancement...
Published: 1/8/2026
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Inventor(s):
Robert Williams
,
Chaeho Moon
,
Sawittree Sahakijpijarn
,
Haiyue Xu
,
Zhengrong Cui
Keywords(s):
Category(s):
Life sciences > Therapeutics > Small molecule
,
Life sciences > Therapeutics > Drug delivery
Novel Selective Activators of Neuronal GIRK Heteromeric Channels Effective in Animal Models of Post-Traumatic Stress Disorder
-collapse: collapse; } INV-18111 Background G protein-gated inwardly rectifying potassium (GIRK) channels, are channels distributed throughout the central nervous system as well as the heart. Pharmacological investigations of GIRK channels, along with studies in animal models, suggest that GIRK activity has an important role in physiological...
Published: 8/20/2025
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Inventor(s):
Ganeshsingh Thakur
,
Diomedes Logothetis
,
Anantha Shekhar
,
Yu Xu
,
Lucas Cantwell
Keywords(s):
Category(s):
Technology Classifications > 1. Life Science > Therapeutics