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Search Results - gloria+ferreira
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Heme Overdrive Rewires Pan-Cancer Cell Metabolism
Competitive Advantages Targets cancer metabolic vulnerability to iron consumption Method is cancer specific Can be used against all cancers as a universal model Summary Iron is essential for cell growth and replication, but aggressive or metastasized cancers often rely on large iron levels, named an “iron-addiction” status....
Published: 4/26/2024
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Inventor(s):
Swamy Adapa
,
Gregory Hunter
,
Gloria Ferreira
,
Hong Yuan (Rays) Jiang
Keywords(s):
Cancer
,
Research Tools
,
Therapeutics
Category(s):
Technology Classifications > Cancer
,
Technology Classifications > Cancer > Cancer Diagnostics
Treatment of Metabolic Diseases with 5-Aminolevulinate Synthase Inhibitors
Competitive Advantages Effectively inhibits ALAS Treats heme biosynthesis disorders and other ALAS related diseases Easy synthesis and purification technique Summary USF scientists have discovered inhibitors against 5-aminolevulinate synthase. This was achieved via a kinetic target -guided synthesis that was extended to multi-fragment screening...
Published: 6/7/2023
|
Inventor(s):
Roman Manetsch
,
Gloria Ferreira
Keywords(s):
Category(s):
Technology Classifications > Medical > Pharmaceuticals
,
Technology Classifications > Medical > Endocrinology
,
Technology Classifications > Medical