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Engineered Chimeric Antigen Receptor (CAR) Microglia-Like Cells for the Treatment of Neurodegenerative Disorders
Brief Description: Engineered stem cell/monocyte/macrophage/glia for the treatment and prevention of neurodegenerative disorders associated with misfolded proteins or glia dyshomeostasis. The present disclosure provides compositions and methods comprising chimeric antigen receptors (CARs) specific for amyloid beta (Aβ) and/or Tau. In certain...
Published: 8/19/2025   |   Inventor(s): Matias Porras Paniagua, Saar Gill, Frederick Christian Bennett
Keywords(s): Cell Therapy, Immunotherapy, Neurodegenerative Diseases
Category(s): Technology Classifications > Therapeutics