Search Results - eric+tran

3 Results Sort By:
T Cell Receptors Targeting KRAS Mutants for Cancer Immunotherapy/Adoptive Cell Therapy
Abstract: Mutations in the Kirsten rat sarcoma viral oncogene homolog (KRAS) gene are among the most common oncogenic drivers in human cancers, affecting nearly a third of all solid tumors. Point mutations in the KRAS gene most frequently affect amino acid position 12, resulting in the substitution of the native glycine (G) residue for other amino...
Published: 4/8/2024   |   Inventor(s): Eric Tran, Yong-Chen Lu, Paul Robbins, Steven Rosenberg, Anna Pasetto, Zhili Zheng
Keywords(s): CANCER, Immunotherapy, Mutated KRAS, Rosenberg, T-cell Receptors
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Oncology, Application > Therapeutics
T-Cell Therapy Against Patient-Specific Cancer Mutations
Abstract: Human cancers contain genetic mutations that are unique to each patient. Some of the mutated peptides are immunogenic, can be recognized by T cells, and therefore, may serve as therapeutic targets. Scientists at the National Cancer Institute's Surgery Branch developed a method to identify T cells that specifically recognize immunogenic mutations...
Published: 4/8/2024   |   Inventor(s): Eric Tran, Yong-Chen Lu, Paul Robbins, Steven Rosenberg
Keywords(s): Cholangiocarcinoma, Immunogenic, Rosenberg, T-cell, Tran
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Therapeutics, TherapeuticArea > Oncology
T-Cell Therapy Against Patient-Specific Cancer Mutations
Abstract: Human cancers contain genetic mutations that are unique to each patient. Some of the mutated peptides are immunogenic, can be recognized by T cells, and therefore, may serve as therapeutic targets. Scientists at the National Cancer Institute's Surgery Branch developed a method to identify T cells that specifically recognize immunogenic mutations...
Published: 4/8/2024   |   Inventor(s): Eric Tran, Paul Robbins, Yong-Chen Lu, Steven Rosenberg
Keywords(s): Cholangiocarcinoma, Immunogenic, T cell, T-cell
Category(s): Collaboration Sought > Licensing, Application > Therapeutics, Collaboration Sought > Collaboration, TherapeuticArea > Oncology