Search Results - dazhi+wang

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Novel Cell Lines and Mouse Model to Study Congenital Heart Defects
Advantages: Mutant mouse lines with various CDK13 mutations Identified cardiac specific CDK13 mutations which mirror heart defect development Genetically modified human induced pluripotent stem cells can be differentiated into different cardiac cell types Provides method for screening potential therapeutic agents for congenital heart defects Summary: Congenital...
Published: 5/9/2025   |   Inventor(s): Joanne Chan, DaZhi Wang
Keywords(s): Animal Models, Cardiovascular Diseases, Cell & Tissue Culture & Engineering
Category(s): Technology Classifications > Medical > Cell & Tissue Engineering
Novel Method to Treat Heart Disease in Duchenne Muscular Dystrophy (DMD) Patients
Advantages: Novel Therapeutic target to treat cardiac dystrophy in DMD: Nox4 Inhibition Potential to reduce fibrosis and improve cardiac function over conventional treatments Potential to combine NOX4 inhibition with dystrophin replacement therapies Summary: Duchenne Muscular Dystrophy (DMD) is a genetic disorder caused by mutations in the...
Published: 4/1/2025   |   Inventor(s): DaZhi Wang, Zhanpeng Huang, Jianming Liu
Keywords(s): Cardiological Diseases Treatment
Category(s): Technology Classifications > Medical > Medical Diagnostics, Technology Classifications > Medical > Therapeutics
2016-177 An Accelerated Phase-Contrast MRI Technique
Summary: UCLA researchers in the Department Radiological Sciences have developed a technique for accelerated phase-contrast MRI, reducing total image acquisition time in the collection of high-resolution data. Background: Phase-contrast Magnetic Resonance Imaging (PC-MRI) is an imaging technique frequently used to visualize patient anatomy for health...
Published: 2/14/2025   |   Inventor(s): Peng Hu, Da Wang
Keywords(s):  
Category(s): Medical Devices > Medical Imaging, Medical Devices > Medical Imaging > MRI
An Improved Phase-Contrast MRI Technique (Case No. 2016-050)
Summary: UCLA researchers in the Department of Radiological Sciences have developed a phase-contrast MRI acquisition technique called Hybrid One- and Two-sided Flow Encoding Only (HOTFEO). Background: 4D flow phase-contrast MRI (PC-MRI) is clinically used to visualize and quantify blood flow and velocity. Temporal resolution and temporal footprint...
Published: 2/14/2025   |   Inventor(s): Peng Hu, Da Wang
Keywords(s): Medical Imaging, MRI
Category(s): Medical Devices > Medical Imaging, Medical Devices > Medical Imaging > MRI