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TYRP-1 Chimeric Antigen Receptor to Treat Melanoma (UCLA Case No. 2020-106)
UCLA researchers in the Departments of Surgical Oncology and Microbiology, Immunology, & Molecular Genetics. have developed a CAR-T therapy that targets TYRP-1 for the treatment of melanoma. BACKGROUND: Immune checkpoint blockade (ICB) is a rapidly emerging immunotherapy approach that uses patients’ immune cells to treat cancer. In contrast...
Published: 9/15/2025   |   Inventor(s): Cristina Puig Saus, Antoni Ribas, Yvonne Chen
Keywords(s): Gene Therapy, Hematology, Immunotherapy, Research Methods
Category(s): Therapeutics > Hematology