Search Results - chemotherapeutic+agents

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Assays for Measuring and Quantifying DNA Damage
Abstract: Exposure to ionizing radiation or agents that induce DNA double-stranded breaks (DSBs), which is one of the most damaging types of lesions in DNA, can result in damage to cells and/or tissues.  Thiscan lead to illness (i.e., Acute Radiation Syndrome, Cancer) or death.  Identifying the amount of exposure to a DNA DSB-causing agent can be useful...
Published: 4/8/2024   |   Inventor(s): Christophe Redon, Yiping Zhang, William Bonner, Jiuping ("Jay") Ji
Keywords(s): and environmental agents, chemotherapeutic agents, DNA damage, ionizing radiation
Category(s): Application > Diagnostics, Collaboration Sought > Collaboration, TherapeuticArea > Oncology, Collaboration Sought > Licensing
Anticancer Compound that Is More Effective and Less Toxic than Available Treatments
Thymidylate Synthase Inhibitor Employs Small Molecules to Inhibit Tumor Cell GrowthThese potential anticancer compounds offer an effective treatment that is less likely to cause resistance and recurrence of cancer and is less toxic to normal tissues than available chemotherapeutic agents. Thymidylate synthase inhibitors are a class of antineoplastic...
Published: 6/27/2021   |   Inventor(s): Lidia Kulemina, Maria Zajac-Kaye
Keywords(s): Anti-Cancer Agents, Cancer, Chemotherapeutic Agents, Drug, inhibitors, Smal molecule, Thymidylate synthase
Category(s): Technology Classifications > Human Health Care > Therapeutics