Search Results - maria+zajac-kaye

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AAV Vectors for Direct Delivery of shRNA into Islet Cells to Treat Pancreatic Cancer
Inhibits Neuroendocrine Tumor Development by Reducing Abnormally High Levels of Thymidylate SynthaseThis AAV vector treatment reduces the oncogenic effect of overexpressed thymidylate synthase to inhibit the development of pancreatic neuroendocrine tumors. Each year doctors diagnose about 1,000 people in the United States with pancreatic neuroendocrine...
Published: 6/27/2021   |   Inventor(s): Kyungah Maeng, Maria Zajac-Kaye
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Therapeutics
Two-Target Treatment that Inhibits Cancer Growth
Targets Thymidylate Synthase and Oncogenic Ras Signaling in Ras Mutant TumorsThis combination strategy contains inhibitors and pharmaceutically acceptable excipients for the treatment of various forms of cancer, such as breast cancer, prostate cancer, brain cancer, or pancreatic cancer. Cancer is the second leading cause of death in the United States....
Published: 6/27/2021   |   Inventor(s): Maria Zajac-Kaye, Rony Francois
Keywords(s): Cancer, Drug combination, KRAS, RAS effectors, Thymidylate synthase
Category(s): Technology Classifications > Human Health Care > Therapeutics
Anticancer Compound that Is More Effective and Less Toxic than Available Treatments
Thymidylate Synthase Inhibitor Employs Small Molecules to Inhibit Tumor Cell GrowthThese potential anticancer compounds offer an effective treatment that is less likely to cause resistance and recurrence of cancer and is less toxic to normal tissues than available chemotherapeutic agents. Thymidylate synthase inhibitors are a class of antineoplastic...
Published: 6/27/2021   |   Inventor(s): Lidia Kulemina, Maria Zajac-Kaye
Keywords(s): Anti-Cancer Agents, Cancer, Chemotherapeutic Agents, Drug, inhibitors, Smal molecule, Thymidylate synthase
Category(s): Technology Classifications > Human Health Care > Therapeutics