Search Results - brian+mckay

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New Method to Screen for Drugs to Treat Age-Related Macular Degeneration

This technology is a method of screening drugs for treatment of age-related macular degeneration (AMD) by culturing retinal pigment epithelium cells (RPE) and subsequently measuring the level of exosome release from the RPE cells. Utilizing this method, the level of exosome release can be correlated with AMD onset and severity. Thus, if a drug can reduce...

Published: 8/8/2024 | Inventor(s): Brian Mckay, Anna Figueroa, Nicole Congrove

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Category(s): Technology Classifications > Healthcare Portfolios > Ophthalmology

Generation of Recombinant Affinity Reagents

Creating protein affinity reagents on a proteome-wide scale is one of the greatest challenges of modern medicine. High quality reagents to capture proteins are necessary for elucidating protein function, developing new molecular diagnostics and even therapeutics. Recent advances in protein discovery will necessitate the need for affinity reagents to...

Published: 5/6/2023 | Inventor(s): Joshua LaBaer, Jie Wang, Ji Qiu, Kevin Gorman, Brian Kay

Keywords(s): Affinity Reagent, Phage display, Protein array

Category(s): Proteomic Assays/Reagents/Tools, Life Science (All LS Techs), Genomic Assays/Reagents/Tools

Diagnostic Analyte to Enrich LINE-1 and Detect LINE-1 Driven Oncologic Disease

This invention is a biomarker model, in which the biomarker detected can be used as a companion diagnostic or for screening and diagnosis of a variety of cancers. The model includes a novel liquid biopsy process that accurately measures biomarkers from blood samples by enriching for cell-derived vesicles shed directly from affected tissues. The data...

Published: 11/16/2023 | Inventor(s): Kenneth Ramos, Emma Bowers, Patrick Silva, Brian Mckay

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Category(s): Technology Classifications > Healthcare Portfolios, Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Life Sciences > Biomarkers