Search Results - application+%3e+diagnostics

495 Results Sort By:
Using Artificial Intelligence To Diagnose Uveitis
Summary: The National Eye Institute seeks research co-development partners and/or licensees for a deep learning algorithm that can identify retinal vasculitis using color fundus images. Description of Technology: Uveitis is caused by inflammation in the eye that can cause pain and reduce vision. The rate of uveitis in the United States is 1 in every...
Published: 8/14/2024   |   Inventor(s): Shilpa Kodati, Jongwoo Kim, Nam Nguyen
Keywords(s):  
Category(s): Application > Diagnostics, Collaboration Sought > Collaboration, TherapeuticArea > Eye / Ear / Nose / Throat
Using Artificial Intelligence To Predict The Risk Of Age-Related Macular Degeneration
Summary: The National Eye Institute seeks research co-development partners and/or licensees for a deep learning algorithm that can predict the probability of progression to late age-related macular degeneration. Description of Technology: In 2024, an estimated 200 million people worldwide suffer from age-related macular degeneration (AMD); projected...
Published: 8/14/2024   |   Inventor(s): Emily Chew, Zhiyong Lu, Tiarnan Keenan, Wai Wong, Qingyu Chen, Elvira Agron
Keywords(s):  
Category(s): Application > Diagnostics, Collaboration Sought > Collaboration, TherapeuticArea > Eye / Ear / Nose / Throat
Methods of Detecting Loss of Heterozygosity and Damaging Mutations in Immune-Related Genes Using Liquid Biopsies
Summary: The National Cancer Institute (NCI) seeks co-development partners and/or licensees for a liquid biopsy diagnostic assay capable of detecting loss of heterozygosity (LOH) and somatic mutations in genes important for antigen processing and presentation and interferon-γ response pathways. Description of Technology: Immunotherapy is...
Published: 7/26/2024   |   Inventor(s): Scott Norberg, Andrew Sinkoe, Xiaolin Wu, James Gulley
Keywords(s):  
Category(s): Application > Diagnostics, Collaboration Sought > Collaboration, TherapeuticArea > Oncology, TherapeuticArea > Immunology
Immunoassay-derived Protein Biomarkers of Atherosclerotic Cardiovascular Disease Risk
This technology includes a combination of 6 protein biomarkers and clinical risk factors to be used as an In Vitro Diagnostic Multivariate Index Assay (IVDMIA) that can improve the identification of individuals at high risk for atherosclerotic cardiovascular disease (ASCVD). Incorporation of novel protein biomarkers of ASCVD risk into risk assessment...
Published: 8/12/2024   |   Inventor(s): Daniel Levy, Martin Larson, Ralph D'Agostino
Keywords(s):  
Category(s): Application > Diagnostics, Application > Research Materials, Collaboration Sought > Licensing, TherapeuticArea > Cardiology
Bivalent Tn5 Complex and its Application to Map Enhancer-Promoter Interactions for Use in Diagnostics
This technology includes a new reagent, termed bivalent Tn5 complex, and applied it to mapping genome-wide enhancer-promoter interactions to be utilized for disease diagnostics. Chromatin structure is critical for regulating transcription in normal development and disease states. In particular, the interaction between enhancers and promotes are essential...
Published: 8/12/2024   |   Inventor(s): Keji Zhao, Qingsong Tang
Keywords(s):  
Category(s): Application > Diagnostics, Collaboration Sought > Licensing, ResearchProducts > Research Equipment
PET Imaging of lntegrin Expression with Suitably Labeled RGD Peptides for Multiple Diagnostic Purposes
This technology includes a number of dimeric RGD peptides which been developed and labeled with various PET isotopes (1BF, 68Ga, and 64Cu) for imaging integrin expression in cancer, inflammation, rheumatoid arthritis, myocardial infarct, stroke and traumatic injury. A number of these peptides have been translated into clinic for diagnosis and therapy...
Published: 8/12/2024   |   Inventor(s): Xiaoyuan (Shawn) Chen, Lixin Lang, Gang NIU
Keywords(s):  
Category(s): Application > Diagnostics, Application > Research Materials, Collaboration Sought > Licensing, ResearchProducts > Research Equipment, TherapeuticArea > Cardiology, TherapeuticArea > Immunology, TherapeuticArea > Neurology
Background-free Imaging by Selective Modulation of Nanodiamond Fluorescence Using a Magnetic Field
This technology includes the use of nanodiamonds to achieve background-free imaging. We present several techniques to reduce or eliminate background florescence by exploiting properties of the fluorescent nanodiamonds. In particular, magnetic field modulation of the fluorescence intensity offers a simple, robust, and easily adaptable method to obtain...
Published: 8/12/2024   |   Inventor(s): Ambika Bumb, Susanta Sarkar, Keir Neuman
Keywords(s):  
Category(s): Application > Diagnostics, Application > Medical Devices, Application > Software / Apps, Collaboration Sought > Licensing, ResearchProducts > Computational models/software, ResearchProducts > Research Equipment
A Highly Efficient Differentiation Protocol for Placental Cells Derived from Human Pluripotent Stem Cells for Diagnostic and Therapeutic Applications
This technology includes in vitro-generated trophectoderm (TE) cells, which are ideal for modeling diseases of the placenta, drug screening, and cell-based therapies. The TE lineage which gives rise to placental cells during early human development. Derivation of definitive placental cells from human pluripotent stem cells in culture remains controversial...
Published: 8/12/2024   |   Inventor(s): William Havel, Jeremy Newkirk, Rita Hadley, Yun Zhou
Keywords(s):  
Category(s): Application > Diagnostics, Application > Research Materials, Application > Therapeutics, Collaboration Sought > Licensing, ResearchProducts > Human Cell Lines, ResearchProducts > Human iPSC Lines
High Relaxivity Mulitivalent Gadolinium on a Peptide Scaffold for Targeted MRI Applications in Disease Diagnosis
This technology includes a peptide containing alternating Alanine and Lys(DOTA-Gd) residues can be used to increase the MRI relaxivity of a peptide. The low molecular weight construct can be appended to proteins, antibodies and peptides to increase MRI signals. This approach offers advantages over previous dendrimeric constructs. The increased MRI signal...
Published: 8/12/2024   |   Inventor(s): Rolf Swenson, Alan Koretsky, Nikorn Pothayee, Deepak Sail
Keywords(s):  
Category(s): Application > Diagnostics, Application > Medical Devices, Application > Research Materials, Collaboration Sought > Licensing
Development of High-Throughput ELISA Based Binding Assays to Detect p53/p63/p73 Family Protein-DNA Interaction in the 96-well Microplate Format for Drug Screening and Other Clinical and Diagnostic Uses
This technology includes ELISA based binding assays of p53, p63 or p73 provide possibilities to validate genome sequencing results, and allow the performance of more in-depth investigation to address scientific mechanisms, as well as to develop applications for high-throughput clinical and diagnosis usages. While quantitative p53 binding assays have...
Published: 8/12/2024   |   Inventor(s): Zhong Chen, Minyoung Jang
Keywords(s):  
Category(s): Application > Diagnostics, Application > Research Materials, ResearchProducts > Research Equipment, TherapeuticArea > Oncology
1 2 3 4 5 6 7 8 9 10 ...