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Search Results - alaji+bah
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Inhibition of ITK by Novel SLP76pTYR Targeted Only ITK Signaling and Enhanced Tregs
Facilitates graft-versus-leukemia effect (GVL) while minimizing graft-versus-host disease (GVHD). Background: Graft versus host disease (GVHD) remains the second leading cause of death following allogeneic hematopoietic stem cell transplant (allo-HCT). In allo-HCT, mature donor T cells in the donor inoculum play a central role in mediating...
Published: 1/8/2025
|
Inventor(s):
Mobin Karimi
,
Alaji Bah
Keywords(s):
Technologies
Category(s):
Campus > Upstate Medical University
,
Technology Classifications
,
Technology Classifications > Healthcare
ABI1 Regulates Transcriptional Activity of Androgen Receptor by Novel DNA and AR Binding Mechanism
Provides new pathways for biomarkers and drug discovery for cancer patients. Background: The gene Abelson interactor protein-1 (ABI1) encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal...
Published: 1/8/2025
|
Inventor(s):
Leszek Kotula
,
Alaji Bah
Keywords(s):
DNA
,
regulation of transcriptional dynamics
,
Technologies
Category(s):
Campus > Upstate Medical University
,
Technology Classifications > Biomedical Science and Engineering
,
Technology Classifications > Healthcare
,
Technology Classifications > Screens and Assays
,
Technology Classifications > Therapeutics and Vaccines