Search Results - aav+vectors

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High Complexity AAV3 Capsid Library for Targeted Human Gene Therapy
Allows Efficient Development of Specialized Vectors for Targeted Gene DeliveryThis adeno-associated virus (AAV) vector library combines tens of millions of actual capsid variants in an AAV3 backbone in order to allow the isolation of specialized variants with increased transduction efficiency and high specificity for particular organs or cell populations,...
Published: 6/27/2021   |   Inventor(s): Sergei Zolotukhin, Damien Marsic
Keywords(s): AAV Vectors, Gene Therapy, Liver
Category(s): Technology Classifications > Human Health Care, Technology Classifications > Human Health Care > Gene Therapy
Panel of Monoclonal Antibodies for Characterization of AAV8 and AAV9 Capsids to Improve Therapeutic Efficacy of AAV Gene-Based Therapy
More Accurately Characterizes AAV8 and AAV9 Capsids for Development of Next Generation Vectors to Evade the Host's Immune Response This panel of antibodies allows better characterization of antigenic epitopes on AAV8 and AAV9 capsids with the goal of mitigating patient immune response to the existing AAV based gene therapy. Adeno-associated viral (AAV)...
Published: 6/27/2021   |   Inventor(s): Mavis Agbandje-McKenna, Kim Van Vliet, Yu-Shan Tseng
Keywords(s): AAV Vectors, Antibody, Antibody-based assay, dot blot, Elisa, Hybridoma
Category(s): Technology Classifications > Research Tools > Biological Materials
Synthetic AAV Capsid Library for Targeted Gene Therapy with Improved Treatment Efficacy
Capsid Library Allows for Gene Therapy Vectors to Target Specific Organs and Tissues This adeno-associated virus (AAV) capsid library allows for targeted gene therapy to specific organs and tissues. Gene therapy is a burgeoning market within the pharmaceutical industry, with a market value projected to reach $500 million by 2020. AAV derived vectors...
Published: 6/27/2021   |   Inventor(s): Sergei Zolotukhin, Mavis Agbandje-McKenna, Damien Marsic
Keywords(s): AAV Vectors, capsid library, combinatorial library, Gene Therapy, Targeted delivery
Category(s): Technology Classifications > Human Health Care > Drug Delivery, Technology Classifications > Human Health Care > Gene Therapy