Search Results - damien+marsic

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Star, Branched, and Graft Polymers in Binders for Inkjet Additive Manufacturing for Personalized Dosage Tablets
THE CHALLENGE A major problem posed by the pharmaceutical industry is giving effective dosages while not giving excessive amounts of a particular drug. An estimated 80% of side effects in humans and animals are a direct result of inaccurate dosing because varying weights in patients. Additive manufacturing has emerged as a very promising method to...
Published: 1/31/2024   |   Inventor(s): Emily Wilts, Timothy Long, Christopher Williams, Da Ma
Keywords(s):  
Category(s): Technology Classifications > Additive Manufacturing, Technology Classifications > Biomedical, Technology Classifications > Chemicals/Materials, Technology Classifications > Pharmacology and Therapeutics
High Complexity AAV3 Capsid Library for Targeted Human Gene Therapy
Allows Efficient Development of Specialized Vectors for Targeted Gene DeliveryThis adeno-associated virus (AAV) vector library combines tens of millions of actual capsid variants in an AAV3 backbone in order to allow the isolation of specialized variants with increased transduction efficiency and high specificity for particular organs or cell populations,...
Published: 6/27/2021   |   Inventor(s): Sergei Zolotukhin, Damien Marsic
Keywords(s): AAV Vectors, Gene Therapy, Liver
Category(s): Technology Classifications > Human Health Care, Technology Classifications > Human Health Care > Gene Therapy
Synthetic AAV Capsid Library for Targeted Gene Therapy with Improved Treatment Efficacy
Capsid Library Allows for Gene Therapy Vectors to Target Specific Organs and Tissues This adeno-associated virus (AAV) capsid library allows for targeted gene therapy to specific organs and tissues. Gene therapy is a burgeoning market within the pharmaceutical industry, with a market value projected to reach $500 million by 2020. AAV derived vectors...
Published: 6/27/2021   |   Inventor(s): Sergei Zolotukhin, Mavis Agbandje-McKenna, Damien Marsic
Keywords(s): AAV Vectors, capsid library, combinatorial library, Gene Therapy, Targeted delivery
Category(s): Technology Classifications > Human Health Care > Drug Delivery, Technology Classifications > Human Health Care > Gene Therapy