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Search Results - aarti+kolluri
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IgG4 Hinge Containing Nanobody-based CARs Targeting GPC3 for Treating Liver Cancer
Abstract: Hepatocellular carcinoma (HCC) is the most common type of liver cancer. Globally, HCC is the sixth most prevalent cancer and third leading cause of cancer-related morbidity. Standard treatment for HCC is not suitable for a large proportion of liver cancer patients. Part of this is because less than a quarter of HCC patients are surgical candidates...
Published: 5/21/2024
|
Inventor(s):
Mitchell Ho
,
Aarti Kolluri
,
Nan Li
Keywords(s):
ANTIBODY
,
cancer therapeutic
,
Chimeric antigen receptors (CARs)
,
Glypican-3 (GPC3)
,
Hepatocellular Carcinoma (HCC)
,
HO
,
IgG4
,
Liver cancer
,
Macrophage
,
NANOBODY
,
Natural Killer (NK) Cell
,
T cell
,
therapeutic
Category(s):
Collaboration Sought > Collaboration
,
Collaboration Sought > Licensing
,
TherapeuticArea > Oncology
,
Application > Therapeutics
y-AApeptide-based long-acting pan-coronavirus fusion inhibitor with dual targets in spike protein and oral bioavailability
Advantages: S-20-1 demonstrates potent inhibitory action, this broad-spectrum activity suggests that S-20-1 could be effective against a wide range of coronaviruses, making it a valuable candidate for pandemic preparedness and management. The research provides insights into the mechanism of action of S-20-1, demonstrating its ability to bind...
Published: 9/25/2023
|
Inventor(s):
Jianfeng Cai
,
Shibo JIANG
,
Lu LU
,
Songyi XUE
,
Xinling WANG
,
Lei WANG
,
Wei XU
,
Shuai XIA
Keywords(s):
Drug Discovery
,
Immunology
Category(s):
Technology Classifications > Medical > Biotechnology
Network-Coded Multiple Access
[Licensing negotiation in progress] [Invitation for Expression of Interest - Deadline: 16 June 2016] Systems and methods include a first wireless local area network (WLAN) system that jointly exploit physical-layer network coding (PNC) and multi-user decoding (MUD) to boost system throughput. This multiple access mode is referred to as Network-Coded...
Published: 1/29/2024
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Inventor(s):
Soung Chang Liew
,
Lu LU
,
Lizhao You
Keywords(s):
Network Coding
,
Wireless Local Area Network
Category(s):
Information and Communications Technology