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Novel Method and Kit Using Monoclonal Antibodies for More Sensitive Detection of Dengue Virus
Following primary dengue virus (DENV) infection, non-structural protein 1 (NS1), a dengue-specific glycoprotein, is present in blood and is easily detected by various assays. However, for any infection thereafter (secondary infection), bioavailability of the glycoprotein greatly reduces sensitivity of DENV detection. Since secondary DENV infection is...
Published: 10/28/2024
|
Inventor(s):
Tesfaye Taye
,
Betty Poole-Smith
,
Elizabeth Hunsperger
Keywords(s):
1NS1
,
ACUTE
,
antibodies
,
Anti-dengue
,
DA4XXX
,
DDXXXX
,
DENV
,
Diagnosis
,
Infection
,
monoclonal
,
Mouse
,
NCEZID/DVBD
,
Non-structural
,
Protein
,
virus
,
VLXXXX
,
WBXXXX
,
WIXXXX
,
XAXXXX
,
XCXXXX
,
XDXXXX
,
XHXXXX
,
YBXXXX
,
YFXXXX
Category(s):
Collaboration Sought > Licensing
,
TherapeuticArea > Immunology
,
ResearchProducts > Research Equipment
,
TherapeuticArea > Infectious Disease
,
ResearchProducts > Antibodies
,
Application > Medical Devices
,
Application > Diagnostics
,
Application > Non-Medical Devices
,
Application > Research Materials