ADGRB3/BAI3-Expressing Cell Lines

Application

ADGRB3/BAI3 expressing human brain tumor cell lines.

Technical Summary

Adhesion G protein coupled receptor B3 (ADGRB3), also called Brain-specific angiogenesis inhibitor 3 (BAI3) is a protein that in humans is encoded by the ADGRB3 gene. Emory University researcher Erwin Van Meir has developed medulloblastoma cell lines DAOY, UW288-1 and PFSK1, stably expressing BAI3 with pLenti-GIII-CMV lentiviral vector and selected with puromycin. BAI3 protein is being investigated in neuroscience, behavior, phagocytosis, myogenesis and cancer.

Developmental Stage

Cell lines are developed and available for license.

Patent Information: