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Search Results - yonghyun+kim
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Human-Derived ECM Hydrogels Produced from Organoids
The Problem: Hydrogel-based tissue scaffolds are designed to mimic native extracellular matrix (ECM) to provide the framework for cell and tissue regeneration for regenerative medicine or research involving human cells. Human ECM is extremely complex, and difficult to reproduce. Current conventional tissue scaffolds are primarily produced from animal...
Published: 10/2/2024
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Inventor(s):
Alexandra Avera
,
Yonghyun Kim
Keywords(s):
Category(s):
Technology Classifications > Healthcare
,
Technology Classifications > Manufacturing
Scalable Biomanufacturing of Tumor Organoids
The Problem: Tumor organoids are miniaturized models of simplified tumor tissue. This new generation of cancer modeling is highly useful for observing cell-to-cell interactions, cell-to-matrix interactions, and cell differentiation. However, the current process for creating organoids is generated by tissue isolated from animals or humans, does not...
Published: 1/30/2024
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Inventor(s):
Alexandra Avera
,
Seung Jo Park
,
Yonghyun Kim
Keywords(s):
Category(s):
Technology Classifications
,
Technology Classifications > Healthcare
,
Technology Classifications > Manufacturing
Nandrolone 17 Beta-Carbonates
Abstract: The available options for male contraceptives are limited. Androgens are administered as part of hormone-based male contraception and have also been used in the treatment of hypogonadism and hormone replacement therapy HRT. Many synthetic androgens require an oil-based delivery vehicle and have limited durations of action. This technology...
Published: 7/1/2024
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Inventor(s):
Richard Blye
,
Hyun Kim
,
Min Lee
Keywords(s):
19-nortestosterone
,
Androgenic Compounds
,
Blye
,
Male Contraceptive
,
Nandrolone
,
National Institute of Child Health and Human Development
,
NICHD
Category(s):
TherapeuticArea > Endocrinology
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Collaboration Sought > Licensing
,
Application > Therapeutics
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Collaboration Sought > Collaboration
,
TherapeuticArea > Reproductive Health
Cell-free RNA biomarkers capable of distinguishing cancer from premalignant disease
Summary Early cancer detection is critical for improving long-term patient survival and highlights a need for new sensitive and minimally-invasive early detection methods. The current technology includes novel sets of cell-free RNA biomarkers that can be used to potentially distinguish between malignant and pre-malignant forms of certain cancers using...
Published: 6/15/2022
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Inventor(s):
Thuy Ngo
,
Hyun Kim
,
Josiah Wagner
,
Breeshey Roskams-Hieter
,
Pavana Anur
Keywords(s):
Diagnostics
,
Diagnostics - Cancer
Category(s):
Diagnostics
Automatic Cell Cluster Dissociator
Separating Cells To Support Healthy & Prolonged Growth THE PROBLEM: Cells, such as stem cells, are frequently grown outside of the body for a variety of applications in research and medicine. As they grow and reach a critical mass, the cells have a tendency of clumping together, which can deprive the center cells of nutrients and oxygen. Thus,...
Published: 2/27/2023
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Inventor(s):
Yonghyun Kim
Keywords(s):
Category(s):
Technology Classifications > Healthcare