Search Results - yiwei+wang

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C41 Analogs

This invention relates generally to neurodegenerative diseases and conditions, such as Alzheimer’s Disease, characterized with dysfunctional energetic function, unregulated microglia phagocytic activity and other related de-regulated biological functions. This invention further relates to methods and compositions for treating such neurodegenerative...

Published: 9/24/2024 | Inventor(s): Wei Wang, Rui Chang, Vijayan Ramachandran, Patrick Ronaldson

Keywords(s):

Category(s): Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Life Sciences > Nutraceuticals, Technology Classifications > Life Sciences > Small Molecules, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Life Sciences > Biologics

Applications of Deuterated Aldehydes and Isonitriles

This innovation is a novel method of synthesizing calcium channel blockers, with applications to extend the half-life of heart disease medications. This can be used as building blocks to create new pharmaceuticals or potentially used to expand the lifespan of current medications. It has applications to site specific calcium-channel blocking that can...

Published: 6/7/2024 | Inventor(s): Christopher Hulme, Wei Wang, Kevin Schofield, Yueteng Zhang

Keywords(s):

Category(s): Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Heart and Vascular

Portable Railroad Track Component Inspection System

Reference #: 01660 The University of South Carolina is offering licensing opportunities for Potable Railroad Track Component Inspection System Background: The Federal Railroad Administration (FRA) stipulates routine track inspections to maintain railroad safety and efficiency. However, conventional manual inspections are not only inefficient and...

Published: 8/21/2024 | Inventor(s): Yu Qian, Yi Wang

Keywords(s):

Category(s): Software and Computing

Bounded Rational Game-Theoretical Modeling of Human Joint Actions with Incomplete Information

Background Physical human-robot interaction (pHRI) is increasingly used in applications where a human model needs to be developed to anticipate future actions including robot-assisted rehabilitation, robotic surgery, and collaborative manufacturing. Modeling humans is a challenging task because of the inherent uncertainties of human decision-making,...

Published: 3/20/2024 | Inventor(s): Wenlong Zhang, Pallavi Shintre, Sunny Amatya, Yiwei Wang

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Category(s): Physical Science, Manufacturing/Construction/Mechanical, Computing & Information Technology

New Deuterated Amino Acid Derivatives

Compositions and methods of making involve the use of alternative acids as reactants instead of carboxylic acids, which produce deuterated amino acids, while carboxylic acids can only synthesize alkyl amino acids. Introducing deuterium to amino acids and derivatives improves biologically active compounds and therapeutics. Modification improves properties...

Published: 6/6/2024 | Inventor(s): Wei Wang, Yue Dong

Keywords(s):

Category(s): Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Materials > Biomaterials, Technology Classifications > Life Sciences

Bioorthogonal Activation of PROTAC Prodrugs

Utilizing proteolysis targeting chimeras (PROTACs) to degrade proteins that are important for tumorigenesis has become a potential therapeutic strategy for cancer. This innovation is an on-demand prodrug strategy called click-release proteolysis targeting chimeras, or “crPROTACs.” The crPROTACs strategy utilizes bioorthogonal chemistry and...

Published: 1/16/2024 | Inventor(s): Wei Wang, Mengyang Chang, Giri Gnawali

Keywords(s):

Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Life Sciences > Small Molecules

A Broad Spectrum Antimicrobial that Synergizes with Copper

University of Arizona researchers have developed an invention that synergizes with copper to kill and prevent further growth of a broad spectrum of pathogens (i.e both Streptococcus pneumoniae and Valley Fever with the potential to work on other pathogens). This therapy does not allow for resistance to be built by the microbes. Published paper with...

Published: 1/5/2024 | Inventor(s): Michael Johnson, Joseph Alvin, Angela Rivera, Wei Wang

Keywords(s):

Category(s): Technology Classifications > Healthcare Portfolios > Infectious Diseases, Technology Classifications > Life Sciences > Therapeutics

Aluminum Oxide Thin Films from Aqueous Precursors

A patented aqueous synthesis route for making high quality alumina thin films of exceptional quality and smoothness Background Aluminum oxide has many desirable properties making it technologically important as a barrier coating, optical film, and as a dieletric thin-film component of electronic devices. The quality of the material varies with...

Published: 6/17/2024 | Inventor(s): Douglas Keszler, Wei Wang

Keywords(s):

Category(s): Engineering

Reconfigurable RF/Digital Hybrid 3D Interconnect

A novel interconnect technology that enables system designers to take better advantage of increased IC power while satisfying energy consumption and space limitations. Background: As the semiconductor industry develops technologies on the nano-scale, interconnect latency is increasing. This places serious limitations on designs, as the input/output...

Published: 2/23/2024 | Inventor(s): Robert Geer, Wei Wang, Tong Jing

Keywords(s): Technologies

Category(s): Campus > SUNY Polytechnic Institute, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Imaging, Technology Classifications > Medical Imaging, Technology Classifications > Optics and Photonics, Technology Classifications > Research Tools and Reagents

Practical Synthesis of C-1 Deuterated 3‑Formylindoles by Organo-photoredox Catalyzed Direct Formylation of Indoles with Deuterated Glyoxylic Acid

This innovation is the synthesis of a Carbon-based indole that can be used in the creation of anti-cancer drugs. Indoles are reagents that can also be used in oncological and renal disease treatment. The new method provides a simple protocol that creates differentiated indoles that have a broad functional tolerance. This uses a more cost-effective agent...

Published: 11/16/2023 | Inventor(s): Wei Wang

Keywords(s):

Category(s): Technology Classifications > Life Sciences, Technology Classifications > Materials, Technology Classifications > Materials > Chemicals

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