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Subunit-Selective NMDAR Antagonists for Treatment of Neurological Disorders
Application GluN2C/2D selective inhibitors that modulate N-methyl-D-aspartic acid receptors (NMDAR) in a subunit-selective manner for treatment of neurological disorders. Key Benefits Specifically targets NMDARs that contain the GluN2C/2D subunit. Higher potency and efficacy compared to previously reported GluN2C/2D-selective modulators. Market...
Published: 8/22/2024   |   Inventor(s): Yao Jing, Stephen Traynelis, Dennis Liotta
Keywords(s): Neuroscience/Pain, Small Molecule
Category(s): TechPub Algolia > Therapeutics, TechPub Algolia > Drug Discovery