Search Results - yao+jing

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From Muscle to Mind: Harnessing the Muscle–Brain Axis with Scalable, Muscle-Derived Extracellular Vesicles to Treat Alzheimer’s Disease
Advantages Harnesses the muscle-brain axis, turning human muscle progenitor cells into a renewable source of brain-targeting therapeutic vesicles. Enables scalable, high-yield vesicle production in a compact bioreactor system. Uses a fully xeno-free process for safer, clinically ready, biocompatible manufacturing. Crosses the blood-brain barrier...
Published: 7/15/2026   |   Updated: 7/15/2026   |   Inventor(s): Wanling Xuan, Yao Yao
Keywords(s): Alzheimer's Disease
Category(s): Technology Classifications > Medical > Neuroscience
Novel Laminin Reporter Mouse Line for in vivo Imaging and Laminin Biology Research (Laminin-mCherry/eGFP+/-) Pre-Cre
Advantages First-ever dual-color laminin reporter mouse line. Enables visualization of laminin-γ1 expression in vivo with high fidelity. mCherry signal replicates endogenous laminin distribution without Cre activation. No background eGFP signal ensures clean baseline imaging. Targets the widely expressed γ1 subunit, enhancing...
Published: 7/1/2026   |   Updated: 10/9/2025   |   Inventor(s): Yao Yao
Keywords(s): Animal Models, Neuroscience, Research Tools
Category(s): Technology Classifications > Research Tools/Copyright > Animal Models
Subunit-Selective NMDAR Antagonists for Treatment of Neurological Disorders
Application GluN2C/2D selective inhibitors that modulate N-methyl-D-aspartic acid receptors (NMDAR) in a subunit-selective manner for treatment of neurological disorders. Key Benefits Specifically targets NMDARs that contain the GluN2C/2D subunit. Higher potency and efficacy compared to previously reported GluN2C/2D-selective modulators. Market...
Published: 1/20/2026   |   Updated: 1/10/2020   |   Inventor(s): Yao Jing, Stephen Traynelis, Dennis Liotta
Keywords(s): Neurology and Pain Treatments, Small Molecule
Category(s): TechPub Algolia > Therapeutics, TechPub Algolia > Drug Discovery