Search Results - xingming+deng

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Small Molecule for Treatment-Resistant Lung Cancer
Application Small molecule agonist for treating cancers involving KRAS mutations. Key Benefits Specifically targets mutant KRAS in non-small-cell lung carcinoma (NSCLC). Selective for mutant KRAS lung cancer cells over normal cells. Non-toxic to normal cells. Market Summary Lung cancer patients with KRAS mutation(s) have a poor prognosis due...
Published: 7/30/2024   |   Inventor(s): Xingming Deng
Keywords(s): Oncology, Small Molecule
Category(s): TechPub Algolia > Drug Discovery, TechPub Algolia > Therapeutics
Small Molecule Inhibitors of Mcl-1 as Anti-Cancer Agent
Application Myeloid cell leukemia 1 (Mcl-1) inhibitor to enhance DNA replication stress sensitivity for cancer therapy. Key Benefits Inhibits DNA repair in cancer cells. Used in combination with existing cancer therapy. Market Summary Chemoresistance occurs when cancer cells develop resistance to chemotherapy drugs, and appearance of chemoresistance...
Published: 8/22/2024   |   Inventor(s): Xingming Deng, Guo Chen, Abu Syed Md Anisuzzaman
Keywords(s): Oncology, Small Molecule
Category(s): TechPub Algolia > Therapeutics, TechPub Algolia > Drug Discovery