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Search Results - victor+ojo
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Targeted Legumain-Cleavable Top1i ADC Platform
Tech Briefs: RSS Drafter said: This technology introduces a legumain-cleavable antibody drug complex (ADC) that delivers topoisomerase inhibitors directly into tumor cells using a short, polar linker design. The platform employs low-potency Top1i derivatives that maintain strong in vivo efficacy while potentially improving safety, offering a balanced...
Published: 12/10/2025
|
Inventor(s):
Lawrence Tumey
,
Nicholas Bianchi
,
Victor Ojo
Keywords(s):
Technologies
Category(s):
Campus > Binghamton University
Dual Payload Antibody Conjugates for Combined Cytotoxic and Immune Stimulatory Cancer Therapy
This invention introduces a dual payload antibody drug conjugate platform that delivers both a potent cytotoxic agent and a TLR7 agonist to tumors with controlled, site specific attachment. By uniting targeted cell killing with localized immune activation in a single biologic, the approach improves therapeutic index, overcomes resistance, and enhances...
Published: 12/9/2025
|
Inventor(s):
Lawrence Tumey
,
Victor Ojo
Keywords(s):
Technologies
Category(s):
Campus > Binghamton University