Search Results - victor+ojo

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Targeted Legumain-Cleavable Top1i ADC Platform
This technology introduces a legumain-cleavable antibody drug complex that delivers a topoisomerase inhibitor directly into tumor cells. Its short, polar linker design enables controlled intracellular release, improving targeting precision and therapeutic potential. In contrast to other related technologies, this invention employs low-potency Top1i...
Published: 4/28/2026   |   Updated: 12/10/2025   |   Inventor(s): Lawrence Tumey, Nicholas Bianchi, Victor Ojo
Keywords(s): Technologies
Category(s): Campus > Binghamton University, Technology Classifications > Antibodies, Technology Classifications > Therapeutics and Vaccines
Dual Payload Antibody Conjugates for Combined Cytotoxic and Immune Stimulatory Cancer Therapy
This invention introduces a dual payload antibody drug conjugate platform that delivers both a potent cytotoxic agent and a TLR7 agonist to tumors with controlled, site specific attachment. By uniting targeted cell killing with localized immune activation in a single biologic, the approach improves therapeutic index, overcomes resistance, and enhances...
Published: 2/13/2026   |   Updated: 11/14/2025   |   Inventor(s): Lawrence Tumey, Victor Ojo
Keywords(s): Technologies
Category(s): Campus > Binghamton University