Search Results - nicholas+bianchi

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Targeted Legumain-Cleavable Top1i ADC Platform
This technology introduces a legumain-cleavable antibody drug complex that delivers a topoisomerase inhibitor directly into tumor cells. Its short, polar linker design enables controlled intracellular release, improving targeting precision and therapeutic potential. In contrast to other related technologies, this invention employs low-potency Top1i...
Published: 4/28/2026   |   Updated: 12/10/2025   |   Inventor(s): Lawrence Tumey, Nicholas Bianchi, Victor Ojo
Keywords(s): Technologies
Category(s): Campus > Binghamton University, Technology Classifications > Antibodies, Technology Classifications > Therapeutics and Vaccines
Resting-State Functional Magnetic Resonance Imaging Derived From Dynamic Perfusion Imaging (Case No. 2023-126)
Intro Sentence: UCLA researchers in the Department of Radiology have developed a novel method for obtaining simultaneous perfusion and functional MRI data from a single MRI acquisition to improve the diagnosis, monitoring, and management of brain tumors and stroke. Background: Advanced magnetic resonance imaging (MRI) techniques are crucial for...
Published: 2/14/2025   |   Updated: 5/30/2024   |   Inventor(s): Benjamin Ellingson, Nicholas Cho, Chencai Wang
Keywords(s):  
Category(s): Medical Devices, Medical Devices > Medical Imaging, Medical Devices > Medical Imaging > MRI, Medical Devices > Monitoring And Recording Systems