Search Results - tumor+formation

2 Results Sort By:
Human Synovial Sarcoma Cell Line A2243
Summary: NCI is seeking parties to non-exclusively license the A2243 human synovial sarcoma cell line. Description of Technology: Synovial sarcoma is a cancer affecting mesenchymal cells in connective tissues. This rare cancer is typically linked to genetic abnormalities or exposure to radiation. Metastatic growth throughout the body can occur primarily...
Published: 4/24/2026   |   Updated: 8/2/2023   |   Inventor(s): Stuart Aaronson, Nelson Ellmore (Estate)
Keywords(s): A2243, Aaronson, Chromosomal Translocation, CONNECTIVE TISSUE, Drug Screening, Human Cell Line, Mesenchymal Cells, Rare Cancer, SSX, Synovial sarcoma, SYT, tumor formation
Category(s): TherapeuticArea > Oncology, Collaboration Sought > Licensing, Application > Research Materials
A Mouse Model of Multiple Endocrine Neoplasia, Type I
The current invention embodies a mouse model which is heterozygous for a null allele at the Men1 locus of murine chromosome 19. Men1 has similar exon-intron organization and amino acid identity compared with its human analog MEN1, which has been implicated in the pathogenesis of multiple endocrine neoplasia, type I (MENI). This mouse model has been...
Published: 8/12/2024   |   Updated: 12/6/2022   |   Inventor(s): Judy Crabtree, Francis Collins
Keywords(s): CC1XXX, CC3XXX, CCXXXX, CXXXXX, endocrine, GB1A3X, GB1AXX, GB1XXX, GB2BXX, GB2XXX, GBXXXX, GCXXXX, GXXXXX, Men1 locus, Model, Mouse, mouse model, MULTIPLE, Multiple endocrine neoplasia, Multiple endocrine neoplasia type 1, Multiple endocrine neoplasia, type 2, murine chromosome 19, NEOPLASIA, tumor formation, TYPE, Zollinger-Ellison syndrome
Category(s): Collaboration Sought > Licensing, Application > Research Materials, Application > Therapeutics, TherapeuticArea > Oncology