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Search Results - tim+(qingbin)+cui
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PTH1R PROTAC
Project ID: TECH-2025-20 Background Every 16 mins a man will die of Prostate cancer. Bone metastasis is the predominant cause of morbidity and mortality in prostate cancer, with > 80 % of lethal cases exhibiting skeletal involvement. Parathyroid hormone-related protein (PTHrP), secreted by tumor cells, binds and activates PTH1R on osteoblasts and...
Published: 6/25/2025
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Inventor(s):
Xiaohong Li
,
Shang Su
,
Tim (Qingbin) Cui
,
Jian-Ting Zhang
Keywords(s):
Category(s):
Oncology
Survivin Inhibitors for Targeted Cancer Treatment
Project ID: TECH-2024-07 Background Prostate cancer is one of the most common cancers and the second-most lethal cancer among men in the United States. While the response to standard androgen deprivation therapy (ADT) is often dramatic, most prostate cancer patients develop resistance to ADT, leading to castration-resistant prostate cancer (CRPC)....
Published: 2/13/2025
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Inventor(s):
Jian-Ting Zhang
,
Jasmine (JingYuan) Liu
,
Tim (Qingbin) Cui
Keywords(s):
Category(s):
Oncology
Treatment for the Prevention of Permanent Vision Loss in Glaucoma Patients
Problem: Glaucoma is the number one cause of irreversible blindness worldwide. High pressure in the eye can lead to optic nerve damage, which can progress to permanent vision loss. For this reason, reduction of intraocular pressure is the main therapeutic mechanism available. Unfortunately, glaucoma can continue to progress even in patients with normalized...
Published: 1/12/2024
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Inventor(s):
Qi Cui
,
Joshua Dunaief
,
Jacob Sterling
Keywords(s):
Ophthalmology
,
Small Molecule
Category(s):
Technology Classifications > Therapeutics