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Search Results - tian+jiang
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Broad-Spectrum Nanozymes for the Treatment of Cancer and Viral Infections
Effectively Degrade RNA in a Non-Sequence Specific Manner and in the Presence of RNase Inhibitors Hollow broad-spectrum nanozymes can degrade intracellular RNA in the presence of ribonuclease inhibitors (RIs) in a non-sequence-specific fashion. RNA translates genetic information into proteins constituting cell structures and crucial molecular regulators,...
Published: 11/16/2023
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Inventor(s):
Yunwei Cao
,
Tian Jiang
Keywords(s):
Category(s):
Technology Classifications > Engineering > Chemical
,
Technology Classifications > Human Health Care > Therapeutics
Advanced Nanozyme Designs for Developing High Selectivity RNA Silencing Therapeutics
Increases Target Selectivity and Enzymatic Activity of Nanozymes and Improves their Synthesis ProcessThese nanozyme designs use a recombinant RNase A loading mechanism strong enough to support high-density surface packing of DNA oligonucleotides, facilitating stable and reproducible synthesis of nanozymes with high target selectivity and enzymatic activity...
Published: 6/27/2021
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Inventor(s):
Yunwei Cao
,
Tian Jiang
Keywords(s):
nanoparticle composite
,
Nanozyme
,
on-off switchable function
,
RNA Interference
Category(s):
Technology Classifications > Engineering > Chemical
,
Technology Classifications > Engineering > Materials
,
Technology Classifications > Human Health Care > Diagnostics
,
Technology Classifications > Human Health Care > Drug Delivery
Bi-Functional RGD Peptide and a Co-Signaling Mechanism to Promote Therapeutic Angiogenesis
Bi-Functional RGD Peptide to Promote Therapeutic Angiogenesis, Treat Ischemic Diseases Technology: While previous studies have focused on the identification of biological ligands to improve the functions of endothelial cells, MUSC and Clemson University researchers have combined modern bioinformatics and a newly established peptide functionalized...
Published: 3/23/2023
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Inventor(s):
Chung-Jen (James) Chou
,
Ying Mei
,
Jia Jia
Keywords(s):
Category(s):
BioPharma