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Search Results - therapeutics+%3e+oncology
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POLQ as a Mediator of Radioresistance in Prostate Cancer (UCLA Case No. 2024-068)
Please contact UCLA Technology Development Group for more information. KEYWORDS: cancer biology, cancer therapy resistance, molecular oncology, drug discovery, radiosensitization, radioresistance mechanisms, predictive biomarkers, prostate cancer
Published: 9/13/2025
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Inventor(s):
Paul Boutros
Keywords(s):
Category(s):
Therapeutics > Oncology
,
Diagnostic Markers
TRP: Sequence of Anti-EMP2 Monoclonal Antibody (UCLA Case No. 2021-369)
Tangible Research Property: Sequence of Anti-EMP2 Monoclonal Antibody. Dr. Madhuri Wadehra's research and discovery efforts are focused on two related themes in tumor biology: understanding the function of a tetraspan protein epithelial membrane protein-2 (EMP2) in tumor progression, and developing therapeutic and diagnostic agents that target...
Published: 9/10/2025
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Inventor(s):
Madhuri Wadehra
Keywords(s):
Category(s):
Life Science Research Tools
,
Therapeutics > Oncology
Bioelectric Neuromodulation Methods for Hematopoiesis Regulation During Chemotherapy (Case No. 2020-382)
Summary: UCLA researchers in the Department of Bioengineering have developed an electrical neuromodulation method to accelerate recovery from deleterious chemotherapy side effects to improve patient outcome. Background: Chemotherapy works by targeting and killing fast-growing cancer cells using anti-cancer drugs. However, because these drugs lack...
Published: 8/21/2025
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Inventor(s):
Wentai Liu
Keywords(s):
algorithmic cancer detection
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Bladder Cancer
,
blood cancers
,
Brain cancer
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Breast Cancer
,
Cancer
,
cancer antigen
,
cancer detection
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Cancer Immunotherapy
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cancer inhibition
,
cancer metabolism
,
Cancer stem cells
,
cancer target
,
castration resistant prostate cancer
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Chemotherapy
,
head and neck cancer
,
lympathic cancers
,
lymphatic cancer
,
Mesenchymal Stem Cell Derived Cancer Cells
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Neuromodulation
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non-small cell lung cancer
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Orthotopic cancer models
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Pancreatic cancer
,
prostate cancer
,
small cell cancer
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small cell lung cancer
,
small cell prostate cancer
Category(s):
Medical Devices
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Medical Devices > Neural Stimulation
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Chemical
,
Electrical
,
Therapeutics
,
Therapeutics > Oncology
Engineered Mucosal-Associated Invariant T (MAIT) Cells and Methods of Making and Using Thereof (UCLA Case No. 2024-055)
UCLA researchers in the Department of Microbiology Immunology and Molecular Genetics have developed a novel platform and methodology for the production of mucosal-associated invariant T (MAIT) cells for therapeutic use in infectious diseases, autoimmune disorders, and cancer. BACKGROUND: Mucosal-associated invariant T (MAIT) cells are a subset of...
Published: 7/31/2025
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Inventor(s):
Lili Yang
Keywords(s):
Category(s):
Therapeutics > Oncology
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Therapeutics > Infectious Diseases
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Therapeutics > Immunology And Immunotherapy
,
Therapeutics > Autoimmune
Improving Immunizations by Suppressing Autophagy in Cells (UCLA Case No. 2023-291)
UCLA researchers in the Department of Molecular, Cell and Developmental Biology have developed methods to suppress autophagy in cells to enhance immune response. These methods target local tumor sites instead of the whole body, thus reducing off-target effects and are applicable to a variety of cancer types, including solid and hematological tumors. BACKGROUND:...
Published: 8/13/2025
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Inventor(s):
Hilary Coller
Keywords(s):
Category(s):
Therapeutics > Oncology
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Therapeutics > Immunology And Immunotherapy
Fish Oil Plus Diet for Prostate Health (UCLA Case No. 2024-092)
UCLA researchers from the Department of Urology have identified a dietary intervention that may slow prostate cancer progression, offering a promising accessible, safe, and non-invasive approach to managing prostate health. BACKGROUND: Prostate cancer is the second most commonly diagnosed cancer in the United States and the fifth leading cause of death...
Published: 7/17/2025
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Inventor(s):
William Aronson
Keywords(s):
Category(s):
Therapeutics > Oncology
,
Therapeutics > Metabolism And Endocrinology
Reverse Engineering Vaccine Antigens (UCLA Case No. 2025-074)
UCLA researchers from the Department of Pediatrics-Allergy/Immunology have developed a novel platform to reverse engineer vaccine antigens for the prevention and treatment of infectious disease and cancer. BACKGROUND: Vaccines function by introducing antigens into a host to stimulate an immune response, providing protection against pathogens and certain...
Published: 7/17/2025
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Inventor(s):
Manish Butte
Keywords(s):
Category(s):
Therapeutics > Oncology
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Therapeutics > Infectious Diseases
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Therapeutics > Vaccines
Modified Hyaluronic Acid Hydrogels Containing Hyaluronidase for the Time‐Controlled and Targeted Release of anti-CTLA-4 and other Therapeutic Antibodies (UCLA Case No. 2016-526)
UCLA researchers from the Department of Medicine have developed a novel therapeutic platform for the administration of low-dose Cytotoxic T-lymphocyte Associated Protein 4 (CTLA-4) antibody for cancer immunotherapy that synergizes with conventional PD-1 therapy while sparing systemic autoimmune toxicity. BACKGROUND: Immune checkpoint inhibitor (CPI)...
Published: 7/17/2025
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Inventor(s):
Michael Roth
,
Airi Harui
Keywords(s):
Cancer Immunotherapy
,
Immunotherapy
Category(s):
Platforms > Drug Delivery
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Therapeutics > Immunology And Immunotherapy
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Therapeutics > Oncology
Analoging and SAR-Based Chemical Approach to Improve the Therapeutic Potency of Small-Molecule Inhibitors of Metastasis (UCLA Case No. 2024-116)
UCLA researchers in the Department of Molecular and Medical Pharmacology have developed an analoging and SAR-based chemical approach to generate novel, safe, and effective small-molecule inhibitors for preventing and treating cancer metastasis. BACKGROUND: The limited understanding of the biological mechanisms underlying metastasis in clear cell renal...
Published: 7/17/2025
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Inventor(s):
Lily Wu
,
Moe Ishihara
,
Robert Damoiseaux
,
Stuart Conway
Keywords(s):
Cancer
,
Metastasis
,
Oncology (Small Molecules, Peptides and Antibodies)
,
Small molecule therapeutics
,
small molecules
Category(s):
Therapeutics > Oncology
KHK Inhibitors as Agents for the Treatment of Cancer and Metabolic Syndrome (UCLA Case No. 2021-222)
UCLA researchers in the Department of Chemistry and Biochemistry have synthesized novel KHK inhibitors that can result in anticancer drugs targeting cancer metabolism. BACKGROUND: Fructose is a naturally occurring sugar found in fruits and vegetables, and is an integral part of the human diet. In comparison to its functional isomer, glucose, which...
Published: 7/17/2025
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Inventor(s):
Heather Christofk
,
Michael Jung
Keywords(s):
Cancer
,
cancer metabolism
,
metabolism
,
Oncology (Small Molecules, Peptides and Antibodies)
,
small molecules
Category(s):
Therapeutics > Oncology
,
Therapeutics > Metabolism And Endocrinology
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