Search Results - joseph+crompton

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Partial Transcription Factor Reprogramming to Rejuvenate Exhausted Tumor-Specific T Cells into Stem-Like Memory T Cells (UCLA Case No. 2024-240)
UCLA researchers from the Department of Surgery have developed a novel approach to partially reprogram exhausted tumor-infiltrating T cells into stem-like memory T cells capable of durable tumor elimination. BACKGROUND: Adoptive cell therapies, such as tumor-infiltrating lymphocyte (TIL) therapy involve isolating T cells from a patient’s tumor,...
Published: 4/1/2026   |   Updated: 3/4/2026   |   Inventor(s): Tyler McCaw, Joseph Crompton
Keywords(s):  
Category(s): Therapeutics > Oncology, Therapeutics > Immunology And Immunotherapy, Therapeutics > Stem Cells And Regenerative Medicine, Life Science Research Tools > Research Methods
Peri-Operative Cancer Therapy to Preserve Anti-Tumor Immune Surveillance (UCLA Case No. 2025-257)
UCLA Researchers from the Department of Surgery have developed a novel approach to preserve anti-tumor immunity in the peri-operative period through modulation of clinically relevant molecular and cellular targets. BACKGROUND: Surgical resection with curative intent is a mainstay of treatment for many solid tumors. However, even when the tumor is macroscopically...
Published: 2/4/2026   |   Updated: 1/12/2026   |   Inventor(s): Tyler McCaw, Joseph Crompton
Keywords(s):  
Category(s): Therapeutics > Oncology, Therapeutics > Immunology And Immunotherapy
Methods and Compositions for Promoting Anti-Tumor Immunity of T Cells (UCLA Case No. 2026-037)
Contact UCLA Technology Development Group to learn more.
Published: 4/9/2026   |   Updated: 9/19/2025   |   Inventor(s): Alexandra Nicoleta Boix De Jesus, Joseph Crompton, Hy Dao
Keywords(s):  
Category(s): Therapeutics > Immunology And Immunotherapy, Therapeutics > Oncology