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A Small Molecule Inhibitor Selective for HDAC11
­HDAC11 is an enzyme which belongs to the Histone Deacetylase (HDAC) class of enzymes. However, HDAC11 has a high defatty-acylase activity while its deacetylation activity is virtually nonexistent. The defatty-acylase activity of HDAC11 is linked to increased interferon I signaling, suggesting that inhibition of HDAC11 can be used to treat diseases...
Published: 8/6/2024   |   Inventor(s): Edward Seto, Hening Lin, Thanh Ho
Keywords(s):  
Category(s): Technology Classifications > Therapeutics > Small Molecules