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Search Results - technology+classifications+%3e+therapeutics+%3e+nanoparticles
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Transformative Nanoparticle-Based Therapy for HIV
HIV/AIDS remains a persistent global epidemic, affecting thousands of new individuals annually. A critical challenge in HIV treatment is the virus's ability to lie dormant in infected T cells, evading immune responses and existing antiretroviral therapies (ART). This latent HIV can reactivate unpredictably, leading to viral rebound and disease progression. Dr....
Published: 12/16/2024
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Inventor(s):
Rohan Fernandes
,
Preethi Balakrishnan
,
Anvitha Shri Ramanujam
,
Alberto Bosque-Pardos
,
Indra Sarabia
,
Carissa Stover
Keywords(s):
Category(s):
Technology Classifications > Therapeutics > Nanoparticles
,
Technology Classifications
,
Technology Classifications > Research Tools > Drug Screening
Prussian Blue Nanoparticles for Targeting Cancer Cells
Immune checkpoint inhibitors have shown promise in cancer treatment by helping the immune system recognize and attack cancer cells. However, many tumors remain resistant to these treatments. To address this challenge, Dr. Rohan Fernandes, a professor at George Washington University, developed a novel patented technology by combining Prussian Blue Nanoparticles...
Published: 12/10/2024
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Inventor(s):
Rohan Fernandes
,
Preethi Balakrishnan
,
Jacob Medina
,
Elizabeth Sweeney
Keywords(s):
Category(s):
Technology Classifications > Therapeutics > Nanoparticles
Engineered Nanoparticles Improve Immune Response to Photothermal Therapy for Cancer
Neuroblastoma is a severe form of cancer and accounts for 15% of all cancer related deaths among children. However, the current modalities of treating this cancer have limited efficacy and are deficient in preventing recurrence. This can be attributed to the heterogeneous and immunosuppressive nature of the cancer coupled with low neoantigen expression. Researchers...
Published: 7/30/2024
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Inventor(s):
Rohan Fernandes
,
Elizabeth Sweeney
,
Juliana Cano-Mejia
Keywords(s):
Category(s):
Technology Classifications > Therapeutics > Nanoparticles
3D printed vascularized tissue scaffold with extracellular matrix triggered growth factor release
Vas-Scaf” is a 3D bio-printed vascularized bone scaffold perfused with osteogenic and angiogenic growth factors. Artificial bone grafts lacking vascularization fail due to poor integration of new tissues with the host and death of interior bone tissues. Bone and blood vessel tissues require different support structures and different biochemical...
Published: 9/11/2024
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Inventor(s):
Haitao Cui
,
Wei Zhu
,
Benjamin Holmes
,
Lijie Zhang
Keywords(s):
Category(s):
Technology Classifications > Therapeutics
,
Technology Classifications > Therapeutics > Nanoparticles
,
Technology Classifications > Industrial or Consumer Tech > Materials