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Generating Mature Cardiomyocytes from Stem Cells with Genetic Engineering
­Cardiomyocytes can be generated in vitro with high throughput and quality at a clinically relevant scale using pluripotent stem cells. However, these cardiomyocytes are phenotypically similar to ones at early fetal stage and often lack the attributes of adult or mature cardiomyocytes which are desirable for drug screening, modelling of adult onset...
Published: 8/1/2024   |   Inventor(s): Emilia Entcheva, Julie Han
Keywords(s):  
Category(s): Technology Classifications > Research Tools > Molecular Engineering, Technology Classifications > Therapeutics > Cells, Technology Classifications > Medical Devices > Regenerative Medicine
Vascularized bone construct using dual 3D bio-printing & regional bioactive factors
­GW researchers generated a vascularized and highly osteogenic bone construct with a biphasic structure using a multiple 3D printing platform. Traditional tissue engineering techniques face major obstacles in creating multiple tissue structures and vascularization of tissues. 3D bioprinting allows for control over the location of cells and biomaterials;...
Published: 7/30/2024   |   Inventor(s): Haitao Cui, Wei Zhu, Lijie Zhang
Keywords(s):  
Category(s): Technology Classifications > Medical Devices > Regenerative Medicine