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Human-Derived ECM Hydrogels Produced from Organoids
The Problem: Hydrogel-based tissue scaffolds are designed to mimic native extracellular matrix (ECM) to provide the framework for cell and tissue regeneration for regenerative medicine or research involving human cells. Human ECM is extremely complex, and difficult to reproduce. Current conventional tissue scaffolds are primarily produced from animal...
Published: 1/30/2024   |   Inventor(s): Alexandra Avera, Yonghyun Kim
Keywords(s):  
Category(s): Technology Classifications > Healthcare, Technology Classifications > Manufacturing
Scalable Biomanufacturing of Tumor Organoids
The Problem: Tumor organoids are miniaturized models of simplified tumor tissue. This new generation of cancer modeling is highly useful for observing cell-to-cell interactions, cell-to-matrix interactions, and cell differentiation. However, the current process for creating organoids is generated by tissue isolated from animals or humans, does not...
Published: 1/30/2024   |   Inventor(s): Alexandra Avera, Seung Jo Park, Yonghyun Kim
Keywords(s):  
Category(s): Technology Classifications, Technology Classifications > Healthcare, Technology Classifications > Manufacturing
Photocurable PVC-Containing for 3D Printing
The Problem: Recycling of polyvinyl chloride (PVC) faces significant hurdles due to the complex composition of post-consumer products and limited collection of PVC. PVC, the third most manufactured plastic in the world, requires recycling methods that rely on energy intensive processes and contaminate recycling streams. A lack of widespread markets...
Published: 12/14/2023   |   Inventor(s): Jason Bara, Pravin Shinde, Ali Al Alshaikh, Kathryn O'Harra
Keywords(s):  
Category(s): Technology Classifications, Technology Classifications > Materials, Technology Classifications > Manufacturing, Technology Classifications > Arts & Media
Intelligent System for Self-Healing Composite Materials
The Problem: Aerospace vehicles endure significant stress resulting from foreign object impacts, thermo-mechanical fatigue, and environmental wear, leading to potential damage such as cracks or the separation of outer layers. Although self-healing systems are available for aerospace vehicles, they require unique sensors and diagnostic systems to monitor...
Published: 10/19/2023   |   Inventor(s): Roy Samit
Keywords(s):  
Category(s): Technology Classifications, Technology Classifications > Transportation, Technology Classifications > Systems & Services, Technology Classifications > Materials, Technology Classifications > Manufacturing
Temperature Sensor on the Chip for Power Semiconductors
­The Problem: Power semiconductors are the fundamental component in power electronic systems. The temperature of a power semiconductor is the major design consideration when designing a power electronic system, however, the temperature impossible to measure during actual operation. This leads to a variety of reliability issues including catastrophic...
Published: 7/30/2024   |   Inventor(s): Nicholas Baker, Andrew Lemmon, Francesco Iannuzzo, ‪Szymon Bęczkowski
Keywords(s):  
Category(s): Technology Classifications > Healthcare, Technology Classifications > Communication, Technology Classifications > Systems & Services, Technology Classifications, Technology Classifications > Manufacturing, Technology Classifications > Materials, Technology Classifications > Energy, Technology Classifications > Transportation
Extraction of Metal Cations Using Glycerol-Based Solvents
The Problem: Lithium is a critical material that has become one of the most important commodities of the 21st Century. As a finite resource, lithium can be costly, and some methods of obtainment can harm the environment by contributing to pollution or requiring large scale mining operations that can lead to catastrophic disturbances of the biodiversity...
Published: 10/19/2023   |   Inventor(s): Jason Bara, Steven Weinman
Keywords(s):  
Category(s): Technology Classifications, Technology Classifications > Materials, Technology Classifications > Manufacturing, Technology Classifications > Transportation
Eco-friendly solvents for organosolv pulping of lignocellulosic biomass into value-added aromatics
The Problem: Lignins are macromolecules derived from wood, are the most abundant, renewable source for aromatic chemicals, and can be transformed into a compound with commercial potential, such as, fine chemicals, pharmaceutical ingredients, and sustainable aviation fuels. Current commercial technologies for chemical pulping of wood chips breakdown...
Published: 10/19/2023   |   Inventor(s): James Sheehan, Jason Bara
Keywords(s):  
Category(s): Technology Classifications, Technology Classifications > Manufacturing, Technology Classifications > Materials, Technology Classifications > Healthcare
Transformative Method for Recycling Esters and Urethanes
­ The Problem: Polyurethane is a versatile polymer used for applications in industries such as footwear, construction materials, and many other products. Polyester, another synthetic material, is commonly used in textiles, packaging, electronics, and other industrial uses. Both these plastics end up as landfill waste and can release harmful chemicals...
Published: 10/19/2023   |   Inventor(s): Jason Bara, Kathryn O'Harra, Mousumi Rani Bepari
Keywords(s):  
Category(s): Technology Classifications, Technology Classifications > Manufacturing, Technology Classifications > Materials
Process for More Efficient and Environmental-Friendly Production of Industrial Solvents
The Problem: Dimethylformamide (DMF) is a common industrial solvent used to manufacture synthetic fibers, plastics, and other chemicals. Tetramethyl Urea (TMU) is another useful solvent for making polymers, resins and additives. Commercial applications for chemicals, Imidazolidin (IMD), can be used in commercial applications such as in pharmaceuticals....
Published: 10/19/2023   |   Inventor(s): James Shogren-Harris, Alexander Minne
Keywords(s):  
Category(s): Technology Classifications, Technology Classifications > Manufacturing, Technology Classifications > Materials, Technology Classifications > Healthcare
Ionene-based Star Polymers
­The Problem: Star polymers exhibit unique physical and chemical properties that can be used as a stabilizing agent in complex formulation, cosmetics, and adhesives, whereas linear polymers can be used as membranes to separate components or used in battery fuel cells. Although both are useful, they have restrictions. They are not easily controllable...
Published: 10/19/2023   |   Inventor(s): Jason Bara, Kathryn O'Harra
Keywords(s):  
Category(s): Technology Classifications > Materials, Technology Classifications, Technology Classifications > Transportation, Technology Classifications > Healthcare, Technology Classifications > Lifestyle & Leisure, Technology Classifications > Manufacturing
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