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Stainless Brush Biopsy for Epithelial Cells

This invention is a new approach to cervical cancer screening that removes the need for staining cervical specimens, leading to significant time and cost savings. Using a brush biopsy technique to collect cells from all layers of the cervix using a specialized brush, the specimen is spread on a slide and imaged using deep ultraviolet (dUVM) technology....

Published: 10/21/2024 | Inventor(s): Rongguang Liang

Keywords(s):

Category(s): Technology Classifications > Healthcare Portfolios > Reproductive Health: Obstetrics & Gynecology, Technology Classifications > Healthcare Portfolios > Women's Health, Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Medical Devices > Diagnostic, Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Imaging & Optics > Microscopy, Spectroscopy, Polarimetry

Inhibition of Exosome Secretion in Triple Negative Breast Cancer

This invention is a new anti-cancer peptide for treatment of Triple-Negative Breast Cancer (TNBC). This new peptide-based therapeutic focuses on blocking of Epidermal Growth Factor Receptor (EGFR) and SNX1. In addition, this peptide blocks the secretion of harmful exosomes that further cancer cell metastasis and modulate the immune environment. Background:...

Published: 10/2/2024 | Inventor(s): Joyce Schroeder, Ryan Hecksel, Abigail Camenisch, Delina Denogean, Josh Lederman

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Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Healthcare Portfolios > Women's Health, Technology Classifications > Life Sciences > Therapeutics

A Diagnostic to Determine Sensitivity to Pharmaceutical Oxytocin and Risk of Postpartum Blood Loss based on Genetic and/or Epigenetic Factors

This invention is for a genetic polymorphism test for assessing the risk of postpartum hemorrhage (PPH) and consequently the need for pharmacological oxytocin. This novel test uses a blood or saliva sample to identify key epigenetic variants linked to oxytocin receptor gene function, ultimately allowing for assessment of responsiveness to the medication. Background:...

Published: 8/20/2024 | Inventor(s): Elise Erickson, Jessica Connelly

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Breast Density Bioelectrical Impedance Device Attachment

This technology is a device which applies bioelectrical impedance (BIA) principles to the breast for an estimate of breast density in order to provide a new screening tool for detection of breast cancer. BIA technology is applied to the limited area of breast as opposed to whole body measurements commonly used to assess adiposity. The goal of the breast...

Published: 8/9/2024 | Inventor(s): Jennifer Bea

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Synthesis of Novel Au(II) Dimers and Investigation of their Potential for Applications in Cancer Treatment

This invention is a method of synthesis of novel Au(II) dimer with pyridine dipyrrolinone (H2PYDP) ligands which demonstrate antiproliferative activity in ovarian cancers. This compound operates with a different mechanism than similar existing drugs allowing for novel combinational drug therapies to be created and tested. Background: It is estimated...

Published: 7/8/2024 | Inventor(s): Elisa Tomat, Iva Habensus, Yu-Shien Sung

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Category(s): Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Healthcare Portfolios > Women's Health

Fecal Containment Obstetric Drape

This technology is an obstetric under-buttocks drape that has an additional flap located above the fluid collection portion for use during labor and delivery in childbirth. This is a one-size-fits all flap that has an adhesive lining at the top that allows for adhesion to the patient’s perineum and across the patient’s back thighs. The flap...

Published: 6/5/2024 | Inventor(s): Cassidy Augustinovich

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Category(s): Technology Classifications > Healthcare Portfolios > Women's Health, Technology Classifications > Medical Devices

Metabolic Screening Methods for Endometrial Cancer

Researchers at the University of Arizona employed cervicovaginal lavage sampling and a global untargeted metabolomic approach to identify potential biomarkers for endometrial cancer. The study's novel approach involved linking cervicovaginal metabolite levels to crucial tumor characteristics such as size, histological grade, and myometrial invasion,...

Published: 3/1/2024 | Inventor(s): Melissa Herbst-Kralovetz, Pawel Laniewski

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Category(s): Technology Classifications > Healthcare Portfolios > Women's Health, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Diagnostics

Phenyllactic Acid: Antimicrobial Activity against Vaginal Microbiota and Cytotoxic Properties on Human Cervical Epithelial Cells

Researchers at the University of Arizona investigated the antimicrobial properties of Phenyllactic Acid (PLA) derivatives against both commensal and Bacterial vaginosis (BV)-associated bacteria, as well as their cytotoxic effects on human cervical epithelial cells. PLA is a broad-spectrum antimicrobial compound produced by vaginal Lactobacillus species;...

Published: 11/6/2024 | Inventor(s): Melissa Herbst-Kralovetz, Pawel Laniewski, Abhijit Date, Phoebe Crossley, Yogesh Sutar

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Category(s): Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Women's Health, Technology Classifications > Healthcare Portfolios > Infectious Diseases

Methods for Guiding Treatments of Vulvovaginal Symptoms and Female Sexual Dysfunction

Multi-omics analysis of cervicovaginal samples has led to the identification of a specific immune mediators, metabolites, and bacteria that are associated with vulvovaginal and sexual health symptoms. These biomarkers hold the potential to be utilized in a non-invasive test that guides the treatment of vulvovaginal symptoms and female sexual dysfunction...

Published: 6/6/2024 | Inventor(s): Melissa Herbst-Kralovetz, Pawel Laniewski

Keywords(s):

Category(s): Technology Classifications > Healthcare Portfolios > Women's Health, Technology Classifications > Healthcare Portfolios > Reproductive Health: Obstetrics & Gynecology, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Therapeutics

A Steerable, Optically Guided System for Detection of Ureteral Injury and Ureteral Catheterization

This technology is a therapeutic and diagnostic one-time-use device to place a ureteral catheter or stent without fluoroscopic guidance. Enhancements to the device may allow detection of injury to the ureter via Optical Coherence Tomography (OCT) and treatment of nephrolithiasis via laser lithotripsy. This small-diameter ureteral catheter or stent comprises...

Published: 1/22/2024 | Inventor(s): John Heusinkveld, Jennifer Barton, Dominique Galvez, Andrew Rocha, William Drake

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Category(s): Technology Classifications > Medical Devices > Diagnostic, Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Healthcare Portfolios > Urology, Technology Classifications > Healthcare Portfolios > Women's Health

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