Stainless Brush Biopsy for Epithelial Cells

This invention is a new approach to cervical cancer screening that removes the need for staining cervical specimens, leading to significant time and cost savings. Using a brush biopsy technique to collect cells from all layers of the cervix using a specialized brush, the specimen is spread on a slide and imaged using deep ultraviolet (dUVM) technology. This image is then analyzed for the presence of cervical cancer. By cutting out the need for complex sample transportation and laboratory processing, this method streamlines the entire screening process, allowing patients to receive accurate test results within 10 minutes, instead of waiting days. This technique covers a larger area of the cervix compared to other methods and provides results that are comparable to a more invasive punch biopsy. The brush biopsy method is also less invasive and less painful than punch biopsy methods and causes less bleeding, making it a more patient-friendly option for cervical cancer diagnosis.

Background: 
This technology aims to address the limitations of current cervical cancer screening methods, which typically involve staining specimens and sending them to a lab for analysis. This process can be time-consuming, expensive, and logistically challenging, often leading to delays in diagnosis and treatment. Current solutions, such as the traditional Pap smear, require laboratory staining and microscopic examination, which can take several days to yield results. These delays can be particularly problematic in low-resource settings, where access to timely diagnostics is critical. The brush biopsy method is a significant improvement over existing methods because it provides rapid and accurate results, saving time and money while also improving access to timely diagnostics, especially in underserved areas. Additionally, the technique allows for a more comprehensive and less invasive sampling of cervical cells, further enhancing the accuracy and patient comfort compared to traditional methods. 

Applications: 

  • Cervical cancer screening
  • General cytology


Advantages: 

  • Immediate testing
  • Faster results
  • Cost effective
  • Less invasive than traditional methods
  • Streamlined process due to no need for sample transportation and laboratory processing
Patent Information: