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A Composite Index to Predict Subsequent Asthma with Clinical Data Obtained During the First Year of Life
This invention is a new index from a simple questionnaire that can predict with reasonable accuracy which children will develop asthma by 5-9 years of age. This involves a composite measure of symptoms of respiratory and non-respiratory illness collected in a research study on the first year of life in order to predict the development of childhood asthma....
Published: 6/25/2025   |   Inventor(s): Fernando Martinez, Dean Billheimer
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary
Small Molecule Therapeutics for SARS and MERS
This technology introduces a potent covalent enzyme inhibitor designed specifically for targeting the cysteine protease, PLpro, a key player in the replication process of SARS coronaviruses like SARS-CoV-2 and MERS. Unlike traditional small molecule inhibitors, this inhibitor offers unparalleled efficacy and specificity, making it a promising candidate...
Published: 2/4/2025   |   Inventor(s): Rui Xiong, Gregory Thatcher, Divakar Indukuri, Kiira Ratia, Li jun Rong
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Infectious Diseases, Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary, Technology Classifications > Life Sciences > Small Molecules, Technology Classifications > Life Sciences > Therapeutics
Fluorinated Poly (β-Amino Ester) Nanoparticle for Highly Efficient and Specific Delivery of Nucleic Acids to the Lung Capillary Endothelium
This technology describes nanoparticles with specific structure design and modification for high efficiency and specific delivery of nucleic acids to the pulmonary endothelial cells. After intravenous administration, the nanoparticles were capable of delivering non-integrating DNA plasmids to lung microvascular endothelial cells but not to other lung...
Published: 12/16/2024   |   Inventor(s): Zicheng Deng, Vladimir Kalinichenko, Donglu Shi
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary, Technology Classifications > Life Sciences > Drug Delivery
Mini-Sensor Suspension System for Supine CO2 Monitoring
University of Arizona researchers have developed a non-invasive device that measures carbon dioxide (CO2) concentration around a person’s face, which has important implications for patients in hospitals and treatment centers. By collecting and analyzing the respiratory gases around a supine subject’s face, the system can provide insights...
Published: 1/3/2024   |   Inventor(s): Yijie Chen, Md Tariqul Islam, Young-Jun Son, Esther Sternberg, Christopher Morton
Keywords(s):  
Category(s): Technology Classifications, Technology Classifications > Healthcare Portfolios, Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary, Technology Classifications > Medical Devices
Covid-19 Time of Intubation Mortality Evaluation (C-TIME)
This invention describes software that uses a scoring system for calculating the probable mortality of patients with COVID-19 pneumonia at the time they require mechanical ventilation. Background: Worldwide there have been over 208 million cases of severe acute respiratory coronavirus 2 (SARS-CoV-2) and over 4.37 million of these cases resulted in...
Published: 5/10/2023   |   Inventor(s): Craig Heise, Robert A. Raschke, Pooja Rangan, Sumit Agarwal, Suresh Uppalapu, Nehan Sher
Keywords(s):  
Category(s): Technology Classifications > Software & Information Technology > Health IT, Technology Classifications > Healthcare Portfolios > Infectious Diseases, Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary, Technology Classifications > Healthcare Portfolios > Emergency Medicine
Method, System and Devices for Defining Respiratory Status
This invention is a system comprising FDA-approved MC10 BioStamp wearable sensors to gauge respiratory health in patients. The sensors are applied directly to the skin and can be used to produce gyroscopic data, including information around muscle activation and sleep. The data can be cross-referenced with observations from a motion capture system....
Published: 6/28/2023   |   Inventor(s): Marvin Slepian
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary
Virtual Reality Simulation for Airway Management
This invention is a dual haptic-virtual reality task training system for medical students and/or professionals learning tracheal tube intubation. This technology combines the current training method and a mannequin with VR/AR and a haptic feedback and force measuring system. By creating a medical training system with a more life-like simulation, users...
Published: 7/30/2024   |   Inventor(s): Jarrod Mosier, Young-Jun Son, David Biffar, Vignesh Subbian, Saurabh Jain, Bijoy Dripta Barua Chowdhury, Thomas Cahir, Eze Ahanonu
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Ear, Nose, & Throat, Technology Classifications > Healthcare Portfolios > Health Education, Medical Training and Operations, Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary, Technology Classifications > Imaging & Optics > Medical Imaging
Innovative Approaches to Optimize the Therapeutic Benefit of Autophagy Inhibition
This invention is a set of novel synthetic compounds that demonstrate autophagy-inhibiting efficacy, useful for cancer and pulmonary hypertension treatment. Background: Autophagy is an evolutionarily conserved lysosomal protein degradation process. Aberrant autophagy plays a role in the pathogenesis of many health conditions including cancer, pulmonary...
Published: 4/3/2023   |   Inventor(s): Jennifer Carew, Steffan Nawrocki, Wei Wang
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary, Technology Classifications > Life Sciences > Therapeutics
Proteins from Asthma-Protective Amish Farm Dust
This technology involves eight proteins that have been identified from fractions of Amish farm dust, which have been shown to protect against asthma in mice models. These eight proteins consist mainly of environmental allergens that can induce an immune response and have the potential to be utilized for allergen immunotherapy to help protect against...
Published: 11/16/2023   |   Inventor(s): Fernando Martinez, Donata Vercelli, Shane Snyder, Erika VonMutius, Mauricius Marques dos Santos, Vadim Pivniouk
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary, Technology Classifications > Life Sciences > Therapeutics
A New Method for Preventing and/or Treating Asthma and Related Respiratory Conditions
This technology is an intranasal and/or inhaled therapeutic that consists of a bacterial extract. Initial studies have shown that it protects against characteristic asthma phenotypes such as airway hypperresponsiveness, bronchoalveolar lavage eosinophillia, and increased expression of type-2 cytokines in the lung. The therapy can protect against various...
Published: 11/16/2023   |   Inventor(s): Donata Vercelli, Fernando Martinez, Vadim Pivniouk, Christian Pasquali, Jacques Bauer
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary
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